Gene Symbol | CRNKL1 |
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Entrez Gene | 51340 |
Alt Symbol | CLF, CRN, Clf1, HCRN, MSTP021, SYF3 |
Species | Human |
Gene Type | protein-coding |
Description | crooked neck pre-mRNA splicing factor 1 |
Other Description | Crn, crooked neck-like 1|SYF3 pre-mRNA-splicing factor|crooked neck homolog|crooked neck pre-mRNA splicing factor-like 1|crooked neck-like 1|crooked neck-like protein 1 |
Swissprots | Q9NQH5 Q9H8F8 Q9BZI9 Q5JY64 Q9BZJ2 Q9GZW7 Q9BZJ1 Q8WYI5 A8K9T4 Q9BZJ0 Q9NYD8 |
Accessions | EAX10206 EAX10207 EAX10208 EAX10209 EAX10210 EAX10211 EAX10212 Q9BZJ0 AA255987 AB016840 BAC53587 AF111802 AAL39004 AF255443 AAF65571 AF318302 AAK01924 AF318303 AAK01925 AF318304 AAK01926 AF318305 AAK01927 AK022908 BAB14303 AK023246 BAB14485 AK023728 BAB14659 AK026342 AK292799 BAF85488 AL832435 CAH10656 BC144222 BC156789 AAI56790 BI550198 DB040881 NM_001278625 NP_001265554 NM_001278626 NP_001265555 NM_001278627 NP_001265556 NM_001278628 NP_001265557 NM_016652 NP_057736 |
Function | Involved in pre-mRNA splicing process. |
Subcellular Location | Nucleus speckle. Cytoplasm. Note=Colocalizes with core spliceosomal snRNP proteins. Also diffusely expressed in cytoplasm. |
Tissue Specificity | Widely expressed. Highly expressed in testis. Not expressed in brain and lung. |
Top Pathways | Spliceosome |
CRN CRISPR/Cas9 KO Plasmid (h) - sc-409937 from Santa Cruz Biotechnology
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CRN HDR Plasmid (h) - sc-409937-HDR from Santa Cruz Biotechnology
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CRN Double Nickase Plasmid (h) - sc-409937-NIC from Santa Cruz Biotechnology
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CRN Double Nickase Plasmid (h2) - sc-409937-NIC-2 from Santa Cruz Biotechnology
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CRN CRISPR Activation Plasmid (h) - sc-409937-ACT from Santa Cruz Biotechnology
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CRN CRISPR Activation Plasmid (h2) - sc-409937-ACT-2 from Santa Cruz Biotechnology
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CRN Lentiviral Activation Particles (h) - sc-409937-LAC from Santa Cruz Biotechnology
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CRN Lentiviral Activation Particles (h2) - sc-409937-LAC-2 from Santa Cruz Biotechnology
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CRN siRNA (h) - sc-77028 from Santa Cruz Biotechnology
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CRN shRNA Plasmid (h) - sc-77028-SH from Santa Cruz Biotechnology
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CRN shRNA (h) Lentiviral Particles - sc-77028-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU103571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6587 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6587 from Sigma-Aldrich
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CRNKL1 siRNA (Human) - CRH9712 from Cohesion Biosciences
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CRNKL1 - MBS8205066 from MyBioSource
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shRNA set against Human Crnkl1 (NM_016652.4) - SHH269721 from Creative biogene
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shRNA set against Human CRNKL1(NM_016652.4) - SHG200167 from Creative biogene
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Human CRNKL1 siRNA - orb270214 from Biorbyt
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CRNKL1 shRNA Plasmid (Human) - CHH9712 from Cohesion Biosciences
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CRNKL1 miRNA 3'UTR clone - MiUTR1H-02435 from Creative biogene
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