Gene Symbol | HHATL |
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Entrez Gene | 57467 |
Alt Symbol | C3orf3, GUP1, MBOAT3, MSTP002, OACT3 |
Species | Human |
Gene Type | protein-coding |
Description | hedgehog acyltransferase-like |
Other Description | GUP1 glycerol uptake/transporter homolog|glycerol uptake/transporter homolog|hedgehog acyltransferase-like protein|membrane bound O-acyltransferase domain containing 3|protein-cysteine N-palmitoyltransferase HHAT-like protein |
Swissprots | Q9HCP6 Q9ULP7 Q8TBG3 |
Accessions | EAW64666 EAW64667 EAW64668 Q9HCP6 AB032999 BAA86487 AB042554 BAB17758 AF109356 AAQ13504 BC022529 AAH22529 BI544867 BI596471 XM_006713274 XP_006713337 XM_006713275 XP_006713338 XM_011533969 XP_011532271 XM_011533970 XP_011532272 XR_940482 XR_940483 XR_940484 NM_020707 NP_065758 NR_027753 |
Function | Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN. {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Heart-specific. {ECO:0000269|PubMed:11374908}. |
GUP1 CRISPR/Cas9 KO Plasmid (h) - sc-412804 from Santa Cruz Biotechnology
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GUP1 HDR Plasmid (h) - sc-412804-HDR from Santa Cruz Biotechnology
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GUP1 Double Nickase Plasmid (h) - sc-412804-NIC from Santa Cruz Biotechnology
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GUP1 Double Nickase Plasmid (h2) - sc-412804-NIC-2 from Santa Cruz Biotechnology
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GUP1 CRISPR Activation Plasmid (h) - sc-412804-ACT from Santa Cruz Biotechnology
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GUP1 CRISPR Activation Plasmid (h2) - sc-412804-ACT-2 from Santa Cruz Biotechnology
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GUP1 Lentiviral Activation Particles (h) - sc-412804-LAC from Santa Cruz Biotechnology
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GUP1 Lentiviral Activation Particles (h2) - sc-412804-LAC-2 from Santa Cruz Biotechnology
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GUP1 siRNA (h) - sc-78153 from Santa Cruz Biotechnology
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GUP1 shRNA Plasmid (h) - sc-78153-SH from Santa Cruz Biotechnology
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GUP1 shRNA (h) Lentiviral Particles - sc-78153-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU066501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10016 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10016 from Sigma-Aldrich
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HHATL siRNA (Human) - CRJ1460 from Cohesion Biosciences
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HHATL - MBS8232677 from MyBioSource
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shRNA set against Human HHATL (NM_020707.3) - SHH311965 from Creative biogene
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HHATL shRNA Plasmid (Human) - CHJ1460 from Cohesion Biosciences
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HHATL miRNA 3'UTR clone - MiUTR3H-09750 from Creative biogene
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