| Gene Symbol |
2810417H13Rik
|
| Entrez Gene |
68026
|
| Alt Symbol |
AA409629, Ns5apt9, Ns5atp9, PAF15, Paf, mKIAA0101, p15(PAF)
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
RIKEN cDNA 2810417H13 gene
|
| Other Description |
HCV NS5A-transactivated protein 9 homolog|PCNA-associated factor|PCNA-associated factor of 15 kDa|p15PAF
|
| Swissprots |
Q9CZ17 Q9CQX4 Q4VAG2 Q9D0A5
|
| Accessions |
EDL26107 Q9CQX4 AK011090 BAB27391 AK011645 AK011835 BAB27868 AK012140 AK013105 BAB28650 AK017673 BAB30866 AK018528 AK134432 AK212319 AK214044 AK214296 AY496943 AAR90858 BC021413 AAH21413 BC096393 AAH96393 XR_379450 NM_026515 NP_080791
|
| Function |
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus. Cytoplasm, perinuclear region {ECO:0000250}. Note=Following DNA damage, localizes to DNA damage sites. Colocalizes with centrosomes in perinuclear region.
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