Gene Symbol | RPRD1A |
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Entrez Gene | 55197 |
Alt Symbol | HsT3101, P15RS |
Species | Human |
Gene Type | protein-coding |
Description | regulation of nuclear pre-mRNA domain containing 1A |
Other Description | CDKN2B-related protein|Cyclin-dependent kinase inhibitor 2B-related protein (p15INK4B-related protein)|cyclin-dependent kinase 2B-inhibitor-related protein|p15INK4B-related protein|regulation of nuclear pre-mRNA domain-containing protein 1A |
Swissprots | A8KA42 Q96FY9 Q7Z5G8 B2RBA3 Q9NVL4 Q96P16 |
Accessions | EAX01365 EAX01366 EAX01367 EAX01368 EAX01369 EAX01370 Q96P16 AF419845 AAL15972 AK001518 BAA91736 AK056810 AK292907 BAF85596 AK314569 BAG37150 AW409855 BC000225 AAH00225 BC010136 AAH10136 BG325568 CA944610 DB444937 DQ892910 ABM83836 EU176720 ABW03521 XM_011526048 XP_011524350 XM_011526049 XP_011524351 XM_011526050 XP_011524352 NM_001303411 NP_001290340 NM_001303412 NP_001290341 NM_001303413 NP_001290342 NM_018170 NP_060640 |
Function | Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle. {ECO:0000269|PubMed:22231121}. |
P15RS CRISPR/Cas9 KO Plasmid (h) - sc-403743 from Santa Cruz Biotechnology
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P15RS HDR Plasmid (h) - sc-403743-HDR from Santa Cruz Biotechnology
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P15RS Double Nickase Plasmid (h) - sc-403743-NIC from Santa Cruz Biotechnology
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P15RS Double Nickase Plasmid (h2) - sc-403743-NIC-2 from Santa Cruz Biotechnology
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P15RS CRISPR Activation Plasmid (h) - sc-403743-ACT from Santa Cruz Biotechnology
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P15RS CRISPR Activation Plasmid (h2) - sc-403743-ACT-2 from Santa Cruz Biotechnology
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P15RS Lentiviral Activation Particles (h) - sc-403743-LAC from Santa Cruz Biotechnology
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P15RS Lentiviral Activation Particles (h2) - sc-403743-LAC-2 from Santa Cruz Biotechnology
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P15RS siRNA (h) - sc-76024 from Santa Cruz Biotechnology
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P15RS shRNA Plasmid (h) - sc-76024-SH from Santa Cruz Biotechnology
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P15RS shRNA (h) Lentiviral Particles - sc-76024-V from Santa Cruz Biotechnology
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P15RS RNAi - H00055197-R01 from Novus Biologicals
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MISSION® esiRNA - EHU072021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18613 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18613 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13983 from Sigma-Aldrich
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RPRD1A siRNA (Human) - CRJ0548 from Cohesion Biosciences
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RPRD1A - MBS8204559 from MyBioSource
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shRNA set against Human RPRD1A (NM_018170.3) - SHH399016 from Creative biogene
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shRNA set against Human P15RS(NM_018170.3) - SHR084498 from Creative biogene
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RPRD1A shRNA Plasmid (Human) - CHJ0548 from Cohesion Biosciences
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RPRD1A miRNA 3'UTR clone - MiUTR1H-07433 from Creative biogene
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