CDKN2B

Gene Symbol	CDKN2B
Entrez Gene	1030
Alt Symbol	CDK4I, INK4B, MTS2, P15, TP15, p15INK4b
Species	Human
Gene Type	protein-coding
Description	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Other Description	CDK inhibitory protein|CDK4B inhibitor|MTS-2|cyclin-dependent kinase 4 inhibitor B|cyclin-dependent kinases 4 and 6 binding protein|multiple tumor suppressor 2|p14-INK4b|p14_CDK inhibitor|p14_INK4B|p15 CDK inhibitor|p15-INK4b|p15_INK4B
Swissprots	P42772 O15125 Q6FI09
Accessions	AAB32712 AAD14049 AAD14186 AAF28397 AAM44859 CAH59951 EAW58596 EAW58597 P42772 AF004819 AAB69989 AF488409 AF488410 AAO49471 AF488411 AF488731 AM392641 CAL37519 AM392962 CAL37840 AM393264 CAL38142 AM393391 CAL38269 BC014469 AAH14469 BC018984 BI560960 CR536529 CAG38766 JQ694046 AFN61601 JQ694047 AFN61602 JQ694048 AFN61603 JX391994 AGC10270 L36844 AAA50282 U17075 AAC50075 NM_004936 NP_004927 NM_078487 NP_511042
Function	Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9230210}. Note=Also found in the nucleus.
Tissue Specificity	Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines. {ECO:0000269|PubMed:9230210}.
Top Pathways	Cell cycle, TGF-beta signaling pathway, Small cell lung cancer, HTLV-I infection, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-CDKN2B-cDNA-Clone - DC03858 from Abgent, a WuXi AppTec company Prices $186.75 Sizes 10 µg Species Human Accession NM_004936

CDKN2B - MBS1268966 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC014469

Human CDKN2B/p15 INK4b Gene ORF cDNA clone in cloning vector - HG11103-M from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid - HG11103-UT from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, N-HA tag - HG11103-NY from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11103-ACG from Sino Biological Species Human

Human CDKN2B Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11103-M-N from Sino Biological Species Human Accession NM_004936.3

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, N-His tag - HG11103-NH from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, C-His tag - HG11103-CH from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11103-NF from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11103-M-F from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11103-NM from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11103-CF from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG11103-ANG from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11103-CM from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11103-ACR from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11103-ANR from Sino Biological Species Human

Human CDKN2B/p15 INK4b Gene ORF cDNA clone expression plasmid, C-HA tag - HG11103-CY from Sino Biological Species Human

Human CDKN2B ORF Clone(NM_004936.3) - CDCR289178 from Creative biogene Species Human

Human CDKN2B ORF clone (NM_078487.2) - CDCR045532 from Creative biogene Species Human

Human CDKN2B ORF Clone (BC014469) - CDCS412027 from Creative biogene Species Human Accession P42772

Human CDKN2B cDNA Clone(NM_078487.2) - CDFG007302 from Creative biogene Species Human

Human CDKN2B cDNA Clone(NM_004936.3) - CDFH003352 from Creative biogene Species Human

Human CDK inhibitory protein Gene - orb91599 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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