| Gene Symbol |
SDK1
|
| Entrez Gene |
221935
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sidekick cell adhesion molecule 1
|
| Other Description |
protein sidekick-1|sidekick homolog 1, cell adhesion molecule
|
| Swissprots |
Q96N44 Q8TEP5 Q8TEN9 Q7Z5N4
|
| Accessions |
EAW87286 EAW87287 EAW87288 Q7Z5N4 AF131799 AK055987 BAB71066 AK055988 AK074077 BAB84903 AK074083 BAB84909 AL833354 AY310398 AAP75619 DB065853 DB454012 XM_011515188 XP_011513490 XM_011515189 XP_011513491 XM_011515190 XP_011513492 NM_001079653 NP_001073121 NM_152744 NP_689957
|
| Function |
Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons. Dysregulation of this protein may play an important role in podocyte dysfunction in HIV- associated nephropathy. {ECO:0000269|PubMed:15213259}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Up-regulated in glomeruli in HIV-associated nephropathy. In diseased glomeruli, significantly overexpressed and the expression is no longer restricted to mesangial cells but includes podocytes and parietal epithelial cells. {ECO:0000269|PubMed:15213259}.
|