| Gene Symbol |
PAPOLG
|
| Entrez Gene |
64895
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
poly(A) polymerase gamma
|
| Other Description |
PAP-gamma|SRP RNA 3' adenylating enzyme/pap2|SRP RNA 3'-adenylating enzyme|neo-PAP|neo-poly(A) polymerase|nuclear poly(A) polymerase gamma|polynucleotide adenylyltransferase gamma
|
| Swissprots |
Q9HAD0 Q969N1 Q59G05 B2RBH4 Q9BWT3 Q9H8L2
|
| Accessions |
AAY14677 AAY14832 EAX00029 EAX00030 EAX00031 EAX00032 EAX00033 EAX00034 Q9BWT3 AB209304 BAD92541 AF312211 AAK83701 AI419423 AJ308101 CAC59751 AK021867 BAB13919 AK023034 BAB14368 AK023544 BAB14604 AK024249 BAB14858 AK314663 BAG37221 AW515951 AY029162 AAK31791 BC016738 AAH16738 BC028593 BC068493 BC110906 AAI10907 BC111701 AAI11702 BC113747 AAI13748 BX647824 DB082179 XM_005264500 XP_005264557 XM_005264501 XP_005264558 XM_011533041 XP_011531343 XR_939713 NM_022894 NP_075045
|
| Function |
Responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA. {ECO:0000269|PubMed:11287430, ECO:0000269|PubMed:11463842}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:11287430, ECO:0000269|PubMed:11463842}.
|
| Tissue Specificity |
Expressed predominantly in testis, and weakly in other tissues. Overexpressed in several tumors. {ECO:0000269|PubMed:11463842}.
|
| Top Pathways |
mRNA surveillance pathway
|