| Gene Symbol | ALDOA |
|---|---|
| Entrez Gene | 226 |
| Alt Symbol | ALDA, GSD12, HEL-S-87p |
| Species | Human |
| Gene Type | protein-coding |
| Description | aldolase A, fructose-bisphosphate |
| Other Description | epididymis secretory sperm binding protein Li 87p|fructose-1,6-bisphosphate triosephosphate-lyase|fructose-bisphosphate aldolase A|lung cancer antigen NY-LU-1|muscle-type aldolase |
| Swissprots | Q6FI10 Q96B15 P04075 Q6FH76 Q9UCN2 Q9BWD9 B4DXI7 |
| Accessions | CAA29654 CAA30979 EAW79933 EAW79934 EAW79935 EAW79936 P04075 AK026577 AK098778 AK301993 BAG63399 AK308495 AK308748 BC000367 AAH00367 BC004333 AAH04333 BC010660 AAH10660 BC012880 AAH12880 BC013614 AAH13614 BC015888 AAH15888 BC016170 AAH16170 BC016800 AAH16800 BE893518 BQ719865 BU855133 BX647566 CB151262 CR536528 CAG38765 CR541880 CAG46678 D28356 BAA05722 DA138954 DA564075 DA893541 DA899482 DB057572 DQ891065 ABM81991 DQ894246 ABM85172 EF036496 ABO65082 EF036497 ABO65083 FJ474908 ACQ91105 M11560 AAA51690 M21190 AAA51697 X05236 CAA28861 XM_011545767 XP_011544069 XM_011545768 XP_011544070 NM_000034 NP_000025 NM_001127617 NP_001121089 NM_001243177 NP_001230106 NM_184041 NP_908930 NM_184043 NP_908932 NM_001243175 |
| Function | Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+). {ECO:0000250}. |
| Top Pathways | Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Biosynthesis of amino acids, Carbon metabolism, Fructose and mannose metabolism |