Gene Symbol | SLC2A2 |
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Entrez Gene | 6514 |
Alt Symbol | GLUT2 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 2 (facilitated glucose transporter), member 2 |
Other Description | glucose transporter type 2, liver|solute carrier family 2, facilitated glucose transporter member 2 |
Swissprots | F8W8V8 B2R936 P11168 Q9UCW9 A8K481 B7Z547 |
Accessions | CBN59495 CBN65426 EAW78498 EAW78499 EAW78500 P11168 AK290846 BAF83535 AK292741 BAF85430 AK298418 BAH12783 AK313622 BAG36383 BC060041 AAH60041 J03810 AAA59514 XM_011513087 XP_011511389 XM_011513088 XP_011511390 XM_011513089 XP_011511391 NM_000340 NP_000331 NM_001278658 NP_001265587 NM_001278659 NP_001265588 |
Function | Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Liver, insulin-producing beta cell, small intestine and kidney. |
Top Pathways | Type II diabetes mellitus, Maturity onset diabetes of the young, Carbohydrate digestion and absorption, Prolactin signaling pathway, Central carbon metabolism in cancer |
Glut2 CRISPR/Cas9 KO Plasmid (h) - sc-400347 from Santa Cruz Biotechnology
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Glut2 HDR Plasmid (h) - sc-400347-HDR from Santa Cruz Biotechnology
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Glut2 Double Nickase Plasmid (h) - sc-400347-NIC from Santa Cruz Biotechnology
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Glut2 Double Nickase Plasmid (h2) - sc-400347-NIC-2 from Santa Cruz Biotechnology
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Glut2 CRISPR Activation Plasmid (h) - sc-400347-ACT from Santa Cruz Biotechnology
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Glut2 CRISPR Activation Plasmid (h2) - sc-400347-ACT-2 from Santa Cruz Biotechnology
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Glut2 Lentiviral Activation Particles (h) - sc-400347-LAC from Santa Cruz Biotechnology
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Glut2 Lentiviral Activation Particles (h2) - sc-400347-LAC-2 from Santa Cruz Biotechnology
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Glut2 siRNA (h) - sc-35495 from Santa Cruz Biotechnology
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Glut2 shRNA Plasmid (h) - sc-35495-SH from Santa Cruz Biotechnology
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Glut2 shRNA (h) Lentiviral Particles - sc-35495-V from Santa Cruz Biotechnology
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Glut2 RNAi - H00006514-R01 from Novus Biologicals
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MISSION® esiRNA - EHU144201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1683 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1683 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10154 from Sigma-Aldrich
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SLC2A2 siRNA (Human) - CRH4409 from Cohesion Biosciences
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SLC2A2 - MBS8222650 from MyBioSource
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shRNA set against Human SLC2A2 (NM_000340.1) - SHH410252 from Creative biogene
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shRNA set against Human SLC2A2(NM_000340.1) - SHL005726 from Creative biogene
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SLC2A2 shRNA Plasmid (Human) - CHH4409 from Cohesion Biosciences
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SLC2A2 miRNA 3'UTR clone - MiUTR1H-09516 from Creative biogene
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