Gene Symbol | GGT7 |
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Entrez Gene | 2686 |
Alt Symbol | D20S101, GGT4, GGTL3, GGTL5, dJ18C9.2 |
Species | Human |
Gene Type | protein-coding |
Description | gamma-glutamyltransferase 7 |
Other Description | GGT 7|gamma-glutamyltransferase 4|gamma-glutamyltransferase-like 3|gamma-glutamyltransferase-like 5|gamma-glutamyltranspeptidase 7|gamma-glutamyltranspeptidase-like 3|glutathione hydrolase 7 |
Swissprots | Q8N899 Q9BYP5 Q9UJ14 Q9BYP6 Q8NF66 |
Accessions | EAW76249 EAW76250 EAW76251 EAW76252 Q9UJ14 AK090413 BAC03394 AK097100 BAC04950 AK124788 BAC85950 AK299494 BAG61452 AY138815 AAN15928 BC033745 AAH33745 BC040030 BC101370 AAI01371 BC101371 AAI01372 BC101372 AAI01373 BC141843 AAI41844 BQ013461 BX401449 CA454346 DA117929 XM_011528780 XP_011527082 XM_011528781 XP_011527083 XM_011528782 XP_011527084 XM_011528783 XP_011527085 XR_936518 XR_936519 NM_178026 NP_821158 |
Function | Cleaves glutathione conjugates. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea. |
Top Pathways | Taurine and hypotaurine metabolism, Glutathione metabolism, Cyanoamino acid metabolism |
GGTL3 CRISPR/Cas9 KO Plasmid (h) - sc-410539 from Santa Cruz Biotechnology
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GGTL3 HDR Plasmid (h) - sc-410539-HDR from Santa Cruz Biotechnology
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GGTL3 Double Nickase Plasmid (h) - sc-410539-NIC from Santa Cruz Biotechnology
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GGTL3 Double Nickase Plasmid (h2) - sc-410539-NIC-2 from Santa Cruz Biotechnology
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GGTL3 CRISPR Activation Plasmid (h) - sc-410539-ACT from Santa Cruz Biotechnology
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GGTL3 CRISPR Activation Plasmid (h2) - sc-410539-ACT-2 from Santa Cruz Biotechnology
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GGTL3 Lentiviral Activation Particles (h) - sc-410539-LAC from Santa Cruz Biotechnology
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GGTL3 Lentiviral Activation Particles (h2) - sc-410539-LAC-2 from Santa Cruz Biotechnology
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GGTL3 siRNA (h) - sc-75129 from Santa Cruz Biotechnology
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GGTL3 shRNA Plasmid (h) - sc-75129-SH from Santa Cruz Biotechnology
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GGTL3 shRNA (h) Lentiviral Particles - sc-75129-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU084141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9266 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9266 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04683 from Sigma-Aldrich
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GGT7 siRNA (Human) - CRH1789 from Cohesion Biosciences
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GGT7 - MBS8235829 from MyBioSource
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shRNA set against Human GGT7 (NM_178026.2) - SHH300894 from Creative biogene
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shRNA set against Human GGTL3(NM_178026.2) - SHH083567 from Creative biogene
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GGT7 shRNA Plasmid (Human) - CHH1789 from Cohesion Biosciences
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GGT7 miRNA 3'UTR clone - MiUTR1H-04024 from Creative biogene
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