MECP2

Gene Symbol	MECP2
Entrez Gene	4204
Alt Symbol	AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT
Species	Human
Gene Type	protein-coding
Description	methyl CpG binding protein 2
Other Description	meCp-2 protein|methyl-CpG-binding protein 2
Swissprots	Q6QHH9 P51608 Q7Z384 O15233
Accessions	AAC08757 ACO25362 AGO46586 AGO46587 AGO46588 AGO46589 AGO46590 AGO46591 AGO46592 AGO46593 AGO46594 AGO46595 AGO46596 AGO46597 AGO46598 AGO46599 AGO46600 AGO46601 AGO46602 AGO46603 AGO46604 AGO46605 AGO46606 AGO46607 AGO46608 AGO46609 AGO46610 AGO46611 AGO46612 AGO46613 AGO46614 AGO46615 AGO46616 AGO46617 AGO46618 AGO46619 AGO46620 AGO46621 AGO46622 AGO46623 AGO46624 AGO46625 AGO46626 AGO46627 AGO46628 AGO46629 AGO46630 AGO46631 AGO46632 AGO46633 AGO46634 AGO46635 AGO46636 AGO46637 AGO46638 AGO46639 AGO46640 AGO46641 AGO46642 AGO46643 AGO46644 AGO46645 AGO46646 AGO46647 AGO46648 AGO46649 AGO46650 AGO46651 AGO46652 AGO46653 AGO46654 AGO46655 AGO46656 AGO46657 AGO46658 AGO46659 AGO46660 AGO46661 AGO46662 AGO46663 AGO46664 AGO46665 AGO46666 AGO46667 AGO46668 AGO46669 AGO46670 AGO46671 AGO46672 AGO46673 AGO46674 AGO46675 AGO46676 AGO46677 AGO46678 AGO46679 AGO46680 AGO46681 AGO46682 AGO46683 AGO46684 AGO46685 AGO46686 AGO46687 AGO46688 AGO46689 AGO46690 AGO46691 AGO46692 AGO46693 AGO46694 AGO46695 AGO46696 AGO46697 AGO46698 AGO46699 AGO46700 AGO46701 AGO46702 AGO46703 AGO46704 AGO46705 AGO46706 AGO46707 AGO46708 AGO46709 AGO46710 AGO46711 AGO46712 AGO46713 AGO46714 AGO46715 AGO46716 AGO46717 AGO46718 AGO46719 AGO46720 AGO46721 AGO46722 AGO46723 AGO46724 AGO46725 AGO46726 AGO46727 AGO46728 AGO46729 AGO46730 AGO46731 AGO46732 AGO46733 AGO46734 AGO46735 AGO46736 AGO46737 AGO46738 AGO46739 AGO46740 AGO46741 AGO46742 AGO46743 AGO46744 AGO46745 AGO46746 AGO46747 AGO46748 AGO46749 AGO46750 AGO46751 AGO46752 AGO46753 AGO46754 AGO46755 AGO46756 AGO46757 AGO46758 AGO46759 AGO46760 AGO46761 AGO46762 AGO46763 AGO46764 AGO46765 AGO46766 AGO46767 AGO46768 AGO46769 AGO46770 AGO46771 AGO46772 AGO46773 AGO46774 AGO46775 AGO46776 AGO46777 AGO46778 AGO46779 AGO46780 AGO46781 AGO46782 AGO46783 AGO46784 AGO46785 AGO46786 AGO46787 AGO46788 AGO46789 AGO46790 AGO46791 AGO46792 AGO46793 AGO46794 AGO46795 AGO46796 AGO46797 AGO46798 AGO46799 AGO46800 AGO46801 AGO46802 AGO46803 AGO46804 AGO46805 AGO46806 AGO46807 AGO46808 AGO46809 AGO46810 AGO46811 AGO46812 AGO46813 AGO46814 AGO46815 AGO46816 AGO46817 AGO46818 AGO46819 AGO46820 AGO46821 AGO46822 AGO46823 AGO46824 AGO46825 AGO46826 AGO46827 AGO46828 AGO46829 AGO46830 AGO46831 AGO46832 AGO46833 AGO46834 AGO46835 AGO46836 AGO46837 AGO46838 AGO46839 AGO46840 AGO46841 AGO46842 AGO46843 AGO46844 AGO46845 AGO46846 AGO46847 AGO46848 AGO46849 AGO46850 AGO46851 AGO46852 AGO46853 AGO46854 AGO46855 AGO46856 AGO46857 AGO46858 AGO46859 AGO46860 AGO46861 AGO46862 AGO46863 AGO46864 AGO46865 AGO46866 AGO46867 AGO46868 AGO46869 AGO46870 AGO46871 AGO46872 AGO46873 AGO46874 AGO46875 AGO46876 AGO46877 AGO46878 AGO46879 AGO46880 AGO46881 AGO46882 AGO46883 AGO46884 AGO46885 AGO46886 AGO46887 AGO46888 AGO46889 AGO46890 AGO46891 AGO46892 AGO46893 AGO46894 AGO46895 AGO46896 AGO46897 AGO46898 AGO46899 AGO46900 AGO46901 AGO46902 AGO46903 AGO46904 CAA64331 EAW72757 EAW72758 EAW72759 P51608 AB209464 BAD92701 AF158180 AAF33023 AJ132917 CAB46446 AK289444 BAF82133 AM392557 CAL37435 AY541280 AAS55455 BC011612 AAH11612 BC031833 AAH31833 BX538060 CAD97991 DQ656049 DQ656051 DQ891939 ABM82865 EU176656 ABW03457 GQ203293 ACS92725 GQ203294 ACS92726 GQ203295 GQ896382 ACY24448 GU479943 ADD17354 GU812285 ADE87881 GU812286 ADE87882 HM020402 ADG26557 HM156732 ADK25710 HM156733 ADK25711 HQ127345 ADM72855 HQ141377 ADW01219 HQ141378 ADW01220 HQ154629 ADM88591 L37298 AAC32737 X89430 CAA61599 X99686 CAA68001 Y12643 CAA73190 XM_005274681 XP_005274738 XM_005274682 XP_005274739 XM_005274683 XP_005274740 XM_006724819 XP_006724882 XM_011531165 XP_011529467 XM_011531166 XP_011529468 NM_001110792 NP_001104262 NM_004992 NP_004983
Function	Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC) (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus. Note=Colocalized with methyl-CpG in the genome.
Tissue Specificity	Present in all adult somatic tissues tested.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MeCP2 full length protein - ab114182 from Abcam Category Protein Source Wheat germ Species Human

Human MeCP2 full length protein - ab196070 from Abcam Category Protein Source HEK 293 cells Species Human

Human MeCP2 full length protein - ab125491 from Abcam Category Protein Source HEK 293 cells Species Human

Human MeCP2 peptide - ab92854 from Abcam Category Peptide

Human MeCP2 protein fragment - ab112319 from Abcam Category Protein Source Wheat germ Species Human

Human MeCP2 protein fragment - ab198107 from Abcam Category Protein Source E. coli Species Human

MeCP2 peptide - ab4912 from Abcam Category Peptide

MeCP2 peptide - ab4913 from Abcam Category Peptide

MECP2 Antibody Blocking Peptide - LS-E1342 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MECP2 Antibody Blocking Peptide - LS-E7433 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MECP2 Blocking Peptide - LS-E7460 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MECP2 Antibody Blocking Peptide - LS-E11491 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MECP2 Antibody Blocking Peptide - LS-E13861 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MECP2 Antibody Blocking Peptide - LS-E7002 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MeCP2 Protein - H00004204-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MeCP2 Protein - H00004204-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MeCP2-Antibody-N-term-S80-Blocking-peptide - BP11975a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MECP2-Antibody-N-term-Blocking-peptide - BP13733a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Phospho-MeCP2S421-Antibody-Blocking-peptide - BP3693a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-MeCP2S80-Antibody-Blocking-peptide - BP3595a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

MECP2 Protein (OPPA00195) - OPPA00195 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source Mammalian system, 293 cells.

Human MECP2 protein - orb168805 from Biorbyt Category Protein Prices $170.00, $289.00, $961.00 Sizes 2 μg, 10 μg, 100 µg Source Mammalian system, 293 cells.

MeCP2 - H00004204-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MeCP2 - H00004204-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MeCP2 - H00004204-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

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