| Gene Symbol |
ZNF22
|
| Entrez Gene |
7570
|
| Alt Symbol |
HKR-T1, KOX15, ZNF422, Zfp422
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger protein 22
|
| Other Description |
krox-26 protein|zinc finger protein 22 (KOX 15)|zinc finger protein KOX15|zinc finger protein Krox-26
|
| Swissprots |
P17026 Q96FM4 Q5T741
|
| Accessions |
AAA36815 AAN15804 EAW86632 EAW86633 P17026 AK291508 BAF84197 AK312278 AU310379 BC010642 AAH10642 BC026193 BC041139 AAH41139 BC053687 AAH53687 BT009806 AAP88808 HQ447131 ADQ31618 S50223 AAB24264 X52346 CAA36572 NM_006963 NP_008894
|
| Function |
Binds DNA through the consensus sequence 5'-CAATG-3'. May be involved in transcriptional regulation and may play a role in tooth formation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
| Tissue Specificity |
In the embryo, expressed in developing craniofacial structures including dental epithelium of maxillary molar tooth organs, tongue epithelium and muscle, and craniofacial bone osteoblasts. In the adult, expressed in mesoderm-derived tissues such as skeletal muscle, heart, kidney and liver. Intermediate expression in spleen, thymus and brain. Low levels in endoderm-derived tissues such as intestine and colon. {ECO:0000269|PubMed:14630903}.
|