| Gene Symbol |
St3gal3
|
| Entrez Gene |
20441
|
| Alt Symbol |
ST3GalIII, ST3N, Siat3, Siat6
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
|
| Other Description |
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase|N-acetyllactosaminide alpha-2,3-sialyltransferase|alpha 2,3-ST 3|beta-galactoside alpha-2,3-sialyltransferase 3|gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase|sialyltransferase 3|sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase)
|
| Swissprots |
Q922X5 P97325
|
| Accessions |
EDL30520 EDL30521 EDL30522 P97325 AK005053 BAB23779 AK013016 BAB28598 AK136442 BAE22980 AK178977 AK187627 AK205193 AK212790 AK215745 AK216530 BB868500 BC006710 AAH06710 BF472945 BQ951077 CO043723 CX240214 X84234 CAA59013 XM_006502890 XP_006502953 XM_006502891 XP_006502954 XM_006502892 XP_006502955 XM_006502893 XP_006502956 XM_006502894 XP_006502957 XM_006502895 XP_006502958 XM_006502896 XP_006502959 XM_006502897 XP_006502960 XM_006502898 XP_006502961 XM_006502899 XP_006502962 XM_006502901 XP_006502964 XR_376301 XR_376302 NM_001161774 NP_001155246 NM_001285520 NP_001272449 NM_001285521 NP_001272450 NM_009176 NP_033202
|
| Function |
Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta- 1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- or NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3- GalNAc.
|
| Subcellular Location |
Membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
|
| Tissue Specificity |
Found in all tissues tested. High expression found in brain, liver, kidney, colon, heart and spleen.
|
| Top Pathways |
Other types of O-glycan biosynthesis, Glycosaminoglycan biosynthesis - keratan sulfate, Glycosphingolipid biosynthesis - lacto and neolacto series
|