| Gene Symbol |
SAMD4A
|
| Entrez Gene |
23034
|
| Alt Symbol |
SAMD4, SMAUG, SMAUG1, SMG, SMGA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sterile alpha motif domain containing 4A
|
| Other Description |
SAM domain-containing protein 4A|protein Smaug homolog 1
|
| Swissprots |
A8MPZ5 Q6PEW4 Q0VA96 Q9UPU9
|
| Accessions |
EAW80644 EAW80645 EAW80646 Q9UPU9 AB028976 BAA83005 AF429970 AAP97302 AK024652 AK025923 AK074716 AL117523 CAB55976 AW129053 BC011489 BC021060 BC021726 AAH21726 BC057838 AAH57838 BC121173 AAI21174 BC121174 AAI21175 BI825501 BX648198 DA393986 NM_001161576 NP_001155048 NM_001161577 NP_001155049 NM_015589 NP_056404
|
| Function |
Acts as a translational repressor of SRE-containing messengers. {ECO:0000269|PubMed:16221671}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16221671}. Cell projection, dendrite {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Enriched in synaptoneurosomes (By similarity). Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1. {ECO:0000250}.
|