| Gene Symbol |
TCEAL1
|
| Entrez Gene |
9338
|
| Alt Symbol |
SIIR, WEX9, p21, pp21
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transcription elongation factor A (SII)-like 1
|
| Other Description |
TCEA-like protein 1|nuclear phosphoprotein p21/SIIR|transcription elongation factor A protein-like 1|transcription elongation factor S-II protein-like 1
|
| Swissprots |
Q15170 Q9UJQ9
|
| Accessions |
AAD17840 EAW54702 Q15170 BC000809 AAH00809 BM784458 BU602495 BX092470 CB053221 CF454849 DQ894373 ABM85299 EU176258 ABW03709 M99701 AAA60149 NM_001006639 NP_001006640 NM_001006640 NP_001006641 NM_004780 NP_004771
|
| Function |
May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context- dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Expressed in all tissues examined. Highly expressed in heart, ovary, prostate and skeletal muscle. Moderately expressed in brain, placenta, testis and small intestine. Weakly expressed in lung, liver and spleen. Expressed in several cancer cell lines. {ECO:0000269|PubMed:10051408}.
|