| Gene Symbol |
GPR87
|
| Entrez Gene |
53836
|
| Alt Symbol |
FKSG78, GPR95, KPG_002
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G protein-coupled receptor 87
|
| Other Description |
G protein-coupled receptor 95|G-protein coupled receptor 87|G-protein coupled receptor 95|orphan GPCR 87
|
| Swissprots |
Q9BY21 Q96JZ8 Q5KU35 Q9BXC2
|
| Accessions |
CAH25954 EAW78808 Q9BY21 AB031548 BAD83583 AF086432 AF237763 AAK01858 AF345566 AAK29069 AF411114 AAL26485 AK027784 BAB55366 BC009540 AAH09540 BC112941 AAI12942 BC117565 AAI17566 BC132888 AAI32889 BC132890 AAI32891 BP226924 EU883576 ACG60650 HQ258209 ADR82963 NM_023915 NP_076404
|
| Function |
Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage. {ECO:0000269|PubMed:17905198, ECO:0000269|PubMed:19602589}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung. {ECO:0000269|PubMed:17905198}.
|