Gene Symbol | LIMK2 |
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Entrez Gene | 3985 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | LIM domain kinase 2 |
Other Description | - |
Swissprots | Q9UFU0 Q96E10 Q7L3H5 Q7KZ80 P53671 A8K6H5 Q99464 |
Accessions | AAB54055 AAB54056 BAA36742 CCQ43329 CCQ43330 EAW59954 EAW59955 EAW59956 EAW59957 EAW59958 EAW59959 P53671 AB451269 BAG70083 AB451396 BAG70210 AK092838 AK093554 BAG52739 AK291640 BAF84329 AK293774 BAG57190 AK299112 BAG61168 AK302553 BAG63822 AK314391 BAG37016 AL117466 CAB55941 AM393090 CAL37968 BC013051 AAH13051 BU553494 BX385507 CR456513 CAG30399 CU013112 CAK54543 CU013400 CAK54842 D45906 BAA08312 D85527 BAA12827 NM_001031801 NP_001026971 NM_005569 NP_005560 NM_016733 NP_057952 |
Function | Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro. {ECO:0000269|PubMed:10436159, ECO:0000269|PubMed:11018042}. |
Subcellular Location | Isoform LIMK2a: Cytoplasm. Nucleus. Note=Isoform LIMK2a is distributed in the cytoplasm and the nucleus. |
Tissue Specificity | Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed. {ECO:0000269|PubMed:8954941}. |
Top Pathways | Axon guidance, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton |
Human LIM kinase 2 full length protein - ab158819 from Abcam
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Human LIM kinase 2 full length protein - ab158820 from Abcam
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Human LIM kinase 2 protein fragment - ab158821 from Abcam
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Recombinant Human LIM kinase 2 Protein - H00003985-P02 from Novus Biologicals
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Recombinant Human LIM kinase 2 Protein - H00003985-Q01 from Novus Biologicals
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Recombinant Human LIM kinase 2 Protein - H00003985-P01 from Novus Biologicals
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Mouse-Limk2-Antibody-C-term-Blocking-Peptide - BP19464b from Abgent, a WuXi AppTec company
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LIMK2 peptide - orb217550 from Biorbyt
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LIMK2 Blocking Peptide - abx062881 from Abbexa
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LIMK2 - H00003985-P01-10 from Acris Antibodies
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LIMK2 - H00003985-P02 from Acris Antibodies
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LIMK2 - H00003985-P02-10 from Acris Antibodies
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LIMK2 - H00003985-P02-25 from Acris Antibodies
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LIMK2 - H00003985-Q01-10 from Acris Antibodies
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LIMK2 - H00003985-Q01-25 from Acris Antibodies
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LIMK2 - P5576 from Acris Antibodies
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LIMK2 fusion protein - Ag3011 from Proteintech Group
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LIMK2 (Phospho-Thr505) Antibody Blocking Peptide - GWB-F3F6A7 from Genway Biotech
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LIMK2 Blocking Peptide - CBP1687 from Cohesion Biosciences
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LIMK2 (D499) Peptide - BS1216P from Bioworld Technology
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LIMK2 (K491) Peptide - BS2284P from Bioworld Technology
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p-LIMK2 (T505) Peptide - BS4117P from Bioworld Technology
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Recombinant Human LIM domain kinase 2(LIMK2) - CSB-YP012953HU CSB-EP012953HU CSB-BP012953HU CSB-MP012953HU from Cusabio
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LIMK2(Phospho-Thr505) antibody blocking peptide - 51127 from Signalway Antibody
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LIMK2 (transcript variant 2b) - TP320400 from Acris Antibodies
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