| Gene Symbol |
Ndnf
|
| Entrez Gene |
68169
|
| Alt Symbol |
A930038C07Rik, epidermacan
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
neuron-derived neurotrophic factor
|
| Other Description |
fibronectin type-III domain-containing protein C4orf31 homolog|protein NDNF
|
| Swissprots |
Q80VN3 Q8C119 Q8BWV6
|
| Accessions |
EDK98778 Q8C119 AK017759 AK020942 AK029210 BAC26349 AK049802 BAC33925 AK086961 BC047154 AAH47154 CK618056 XM_006506528 XP_006506591 NM_172399 NP_765987
|
| Function |
Promotes neuron migration, growth and survival as well as neurite outgrowth (By similarity). Promotes matrix assembly and cell adhesiveness. {ECO:0000250, ECO:0000269|PubMed:18757743}.
|
| Subcellular Location |
Secreted {ECO:0000269|PubMed:18757743}.
|
| Tissue Specificity |
Expressed in brain and spinal cord with no expression detected in heart, kidney or liver. Expressed by neurons but not by astrocytes. In the brain, detected in the cerebrum, cerebellum and olfactory bulbs. In the cerebral cortex, highly expressed in Cajal-Retzius cells. Also expressed in hippocampal neurons and in Purkinje and granule cells of the cerebellum (at protein level). {ECO:0000269|PubMed:20969804}.
|