Gene Symbol | DDC |
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Entrez Gene | 1644 |
Alt Symbol | AADC |
Species | Human |
Gene Type | protein-coding |
Description | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
Other Description | aromatic-L-amino-acid decarboxylase |
Swissprots | Q75MJ6 Q5W5T9 C9IYA0 Q16723 E7EU95 E7ER62 P20711 |
Accessions | AAB23675 AAD40482 AAS00092 AAS01995 EAL23898 EAW60970 EAW60971 EAW60972 P20711 AJ310724 CAC84071 AK298321 BAG60574 AK298392 BAG60627 AU310260 AW772056 BC000485 AAH00485 BC008366 AAH08366 BM713211 BT007009 AAP35655 CD013934 CD013935 CD013936 CD013937 CD013938 CR456724 CAG33005 DC362073 EU176304 ABW03755 M76180 AAA58437 M88700 AAA20894 XM_005271745 XP_005271802 XM_011515161 XP_011513463 NM_000790 NP_000781 NM_001082971 NP_001076440 NM_001242886 NP_001229815 NM_001242887 NP_001229816 NM_001242888 NP_001229817 NM_001242889 NP_001229818 NM_001242890 NP_001229819 |
Function | Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. |
Top Pathways | Dopaminergic synapse, Alcoholism, Cocaine addiction, Amphetamine addiction, Phenylalanine metabolism |
DDC CRISPR/Cas9 KO Plasmid (h) - sc-403811 from Santa Cruz Biotechnology
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DDC HDR Plasmid (h) - sc-403811-HDR from Santa Cruz Biotechnology
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DDC Double Nickase Plasmid (h) - sc-403811-NIC from Santa Cruz Biotechnology
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DDC Double Nickase Plasmid (h2) - sc-403811-NIC-2 from Santa Cruz Biotechnology
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DDC CRISPR Activation Plasmid (h) - sc-403811-ACT from Santa Cruz Biotechnology
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DDC CRISPR Activation Plasmid (h2) - sc-403811-ACT-2 from Santa Cruz Biotechnology
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DDC Lentiviral Activation Particles (h) - sc-403811-LAC from Santa Cruz Biotechnology
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DDC Lentiviral Activation Particles (h2) - sc-403811-LAC-2 from Santa Cruz Biotechnology
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DDC siRNA (h) - sc-60515 from Santa Cruz Biotechnology
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DDC shRNA Plasmid (h) - sc-60515-SH from Santa Cruz Biotechnology
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DDC shRNA (h) Lentiviral Particles - sc-60515-V from Santa Cruz Biotechnology
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Dopa Decarboxylase/DDC RNAi - H00001644-R01 from Novus Biologicals
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Dopa Decarboxylase/DDC RNAi - H00001644-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN1899 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1899 from Sigma-Aldrich
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DDC siRNA (Human) - CRH1158 from Cohesion Biosciences
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DDC - MBS829684 from MyBioSource
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shRNA set against Human DDC (NM_000790.3) - SHH275589 from Creative biogene
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shRNA set against Human DDC(NM_000790.3) - SHG225663 from Creative biogene
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DDC shRNA Plasmid (Human) - CHH1158 from Cohesion Biosciences
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DDC miRNA 3'UTR clone - MiUTR1H-02707 from Creative biogene
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