| Gene Symbol |
SYNJ1
|
| Entrez Gene |
8867
|
| Alt Symbol |
INPP5G, PARK20
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
synaptojanin 1
|
| Other Description |
inositol 5'-phosphatase (synaptojanin 1)|synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1|synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1|synaptojanin-1|synaptojanin-1, polyphosphoinositide phosphatase
|
| Swissprots |
O94984 Q4KMR1 O43426 O43425
|
| Accessions |
CAR81404 CBX84866 EAX09863 EAX09864 O43426 AB020717 BAA74933 AF009039 AAC51921 AF009040 AAC51922 AK295706 BAG58552 AK304044 BAG64955 AK307762 AL109818 BC019630 AAH19630 BC067231 BC098395 AAH98395 BC136603 AAI36604 BP350252 CA944966 DB071394 DQ421853 ABD77575 NM_001160302 NP_001153774 NM_001160306 NP_001153778 NM_003895 NP_003886 NM_203446 NP_982271
|
| Function |
Inositol 5-phosphatase which has a role in clathrin- mediated endocytosis.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Concentrated at clathrin-coated endocytic intermediates in nerve terminals. Isoform 1 is more enriched than isoform 2 in developing brain as well as non-neuronal cells. Isoform 2 is very abundant in nerve terminals.
|
| Top Pathways |
Inositol phosphate metabolism, Phosphatidylinositol signaling system
|