Gene Symbol | UNC45B |
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Entrez Gene | 146862 |
Alt Symbol | CMYA4, CTRCT43, SMUNC45, UNC45 |
Species | Human |
Gene Type | protein-coding |
Description | unc-45 homolog B (C. elegans) |
Other Description | UNC-45B|cardiomyopathy associated 4|protein unc-45 homolog B|striated muscle UNC45 |
Swissprots | Q495Q8 Q8IWX7 Q495Q9 |
Accessions | EAW80162 EAW80163 EAW80164 Q8IWX7 AF539794 AAO13384 AK095929 AL832355 AL833281 BC101062 AAI01063 BC101063 AAI01064 BX647642 XM_005257926 XP_005257983 NM_001033576 NP_001028748 NM_001267052 NP_001253981 NM_001308281 NP_001295210 NM_173167 NP_775259 |
Function | Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. |
UNC45B CRISPR/Cas9 KO Plasmid (h) - sc-407188 from Santa Cruz Biotechnology
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UNC45B HDR Plasmid (h) - sc-407188-HDR from Santa Cruz Biotechnology
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UNC45B Double Nickase Plasmid (h) - sc-407188-NIC from Santa Cruz Biotechnology
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UNC45B Double Nickase Plasmid (h2) - sc-407188-NIC-2 from Santa Cruz Biotechnology
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UNC45B CRISPR Activation Plasmid (h) - sc-407188-ACT from Santa Cruz Biotechnology
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UNC45B CRISPR Activation Plasmid (h2) - sc-407188-ACT-2 from Santa Cruz Biotechnology
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UNC45B Lentiviral Activation Particles (h) - sc-407188-LAC from Santa Cruz Biotechnology
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UNC45B Lentiviral Activation Particles (h2) - sc-407188-LAC-2 from Santa Cruz Biotechnology
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UNC45B siRNA (h) - sc-94067 from Santa Cruz Biotechnology
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UNC45B shRNA Plasmid (h) - sc-94067-SH from Santa Cruz Biotechnology
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UNC45B shRNA (h) Lentiviral Particles - sc-94067-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU047001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22498 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22498 from Sigma-Aldrich
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UNC45B siRNA (Human) - CRJ5500 from Cohesion Biosciences
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UNC45B - MBS8237620 from MyBioSource
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shRNA set against Human UNC45B (NM_173167.2) - SHH440536 from Creative biogene
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shRNA set against Human UNC45B(NM_001033576.1) - SHL114686 from Creative biogene
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shRNA set against Human UNC45B(NM_173167.2) - SHL114786 from Creative biogene
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UNC45B shRNA Plasmid (Human) - CHJ5500 from Cohesion Biosciences
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UNC45B miRNA 3'UTR clone - MiUTR1H-11013 from Creative biogene
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UNC45B miRNA 3'UTR clone - MiUTR1H-11014 from Creative biogene
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