Gene Symbol | IL4I1 |
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Entrez Gene | 259307 |
Alt Symbol | FIG1, LAAO, LAO |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 4 induced 1 |
Other Description | Fig-1 protein|IL4-induced protein 1|L-amino-acid oxidase|interleukin four induced 1 |
Swissprots | Q96RQ8 Q1WMJ3 Q4GZN2 Q8TEM5 Q6P2Q3 Q96RQ9 Q4GZN1 |
Accessions | AAK73363 EAW52574 EAW52575 Q96RQ9 AF293462 AAK73362 AJ880386 CAI54291 AJ880387 CAI54292 AJ880388 CAI54293 AJ880389 AY358933 AAQ89292 BC026103 BC064378 AAH64378 BC090852 AAH90852 BC131625 AAI31626 BQ672052 DQ079587 AAZ32711 DQ079588 AAZ32712 DQ079589 AAZ32713 NM_001258017 NP_001244946 NM_001258018 NP_001244947 NM_152899 NP_690863 NM_172374 NP_758962 NR_047577 |
Function | Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity). {ECO:0000250}. |
Subcellular Location | Isoform 1: Lysosome {ECO:0000250}. |
Tissue Specificity | Isoform 1 is primarily found in immune tissues. {ECO:0000269|PubMed:12031486}. |
Top Pathways | Cysteine and methionine metabolism, Phenylalanine metabolism, Tyrosine metabolism, Tryptophan metabolism, Alanine, aspartate and glutamate metabolism |
IL-4I1 CRISPR/Cas9 KO Plasmid (h) - sc-415270 from Santa Cruz Biotechnology
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IL-4I1 HDR Plasmid (h) - sc-415270-HDR from Santa Cruz Biotechnology
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IL-4I1 Double Nickase Plasmid (h) - sc-415270-NIC from Santa Cruz Biotechnology
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IL-4I1 Double Nickase Plasmid (h2) - sc-415270-NIC-2 from Santa Cruz Biotechnology
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IL-4I1 CRISPR Activation Plasmid (h) - sc-415270-ACT from Santa Cruz Biotechnology
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IL-4I1 CRISPR Activation Plasmid (h2) - sc-415270-ACT-2 from Santa Cruz Biotechnology
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IL-4I1 Lentiviral Activation Particles (h) - sc-415270-LAC from Santa Cruz Biotechnology
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IL-4I1 Lentiviral Activation Particles (h2) - sc-415270-LAC-2 from Santa Cruz Biotechnology
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IL-4I1 siRNA (h) - sc-97737 from Santa Cruz Biotechnology
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IL-4I1 shRNA Plasmid (h) - sc-97737-SH from Santa Cruz Biotechnology
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IL-4I1 shRNA (h) Lentiviral Particles - sc-97737-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10633 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10633 from Sigma-Aldrich
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IL4I1 siRNA (Human) - CRJ6819 from Cohesion Biosciences
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IL4I1 - MBS8235087 from MyBioSource
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shRNA set against Human IL4I1 (NM_152899.1) - SHH318993 from Creative biogene
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Human IL4I1 siRNA - orb277320 from Biorbyt
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IL4I1 shRNA Plasmid (Human) - CHJ6819 from Cohesion Biosciences
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IL4I1 miRNA 3'UTR clone - MiUTR1H-04923 from Creative biogene
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