| Gene Symbol |
APOB
|
| Entrez Gene |
338
|
| Alt Symbol |
FLDB, LDLCQ4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
apolipoprotein B
|
| Other Description |
apo B-100|apoB-100|apoB-48|apolipoprotein B (including Ag(x) antigen)|apolipoprotein B-100|apolipoprotein B48|mutant Apo B 100
|
| Swissprots |
Q9UMN0 Q13788 Q4ZG63 P78481 Q13787 P78480 Q13786 Q7Z600 O00502 Q13779 Q53QC8 Q13785 P78479 P04114
|
| Accessions |
AAA53373 AAA53374 AAB00481 AAB31094 AAB31095 AAB60718 AAN86590 AAO49814 AAP72970 AAX88848 AAX93246 ACN81311 ADM85890 ADM85891 ADM85892 ADM85893 AGQ46318 AGQ46319 AGQ46320 CAA28558 CAA28559 CAA28560 CAA28561 CCQ42981 EAX00801 EAX00802 EAX00803 P04114 AB208846 BAD92083 AJ399514 AK290844 BAF83533 BC051278 AAH51278 GU014832 ACX32319 HM487065 ADN03360 J02610 AAA35549 K03175 AAA51759 M10374 AAA51750 M12413 AAA51742 M12480 AAA51751 M12681 AAA51753 M14081 AAA51752 M14162 AAB04636 M15421 AAA51758 M17367 AAA51741 M17779 AAA51755 M18036 AAA51754 M18471 AAA35541 M19734 AAA35544 M31030 AAA51756 M36676 AAA35548 X03045 CAA26850 X03324 CAA27043 X03325 CAA27044 X03326 CAA27045 X04506 CAA28191 X04714 CAA28420 XM_011532809 XP_011531111 NM_000384 NP_000375
|
| Function |
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:22580899}. Secreted {ECO:0000269|PubMed:22580899}.
|
| Top Pathways |
Fat digestion and absorption, Vitamin digestion and absorption
|