Gene Symbol | CHRD |
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Entrez Gene | 8646 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | chordin |
Other Description | - |
Swissprots | Q9H2W8 Q9P0Z4 Q6UW83 Q9P0Z3 Q9H2X0 O95254 Q2M1I8 Q9H2W9 Q9P0Z2 Q9H2D3 Q9P0Z5 |
Accessions | AAF70236 AAF70237 AAF70238 AAF70239 EAW78239 EAW78240 EAW78241 EAW78242 Q9H2X0 AB208947 BAD92184 AF038198 AF076612 AAC69835 AF209928 AAG35767 AF209929 AAG35768 AF209930 AAG35769 AF283325 AAG35784 AK074147 BAB84973 AK293456 BAH11513 AK295632 BAH12133 AK296316 BAH12312 AK300213 BAH13240 AK300476 BAH13292 AY358926 AAQ89285 BC029879 AAH29879 BC112345 AAI12346 XM_011513254 XP_011511556 XM_011513255 XP_011511557 XM_011513256 XP_011511558 XR_924203 NM_001304472 NP_001291401 NM_001304473 NP_001291402 NM_001304474 NP_001291403 NM_003741 NP_003732 NR_130747 NM_177978 NM_177979 |
Function | Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Expressed at the highest level in liver. |
Top Pathways | TGF-beta signaling pathway |
chordin CRISPR/Cas9 KO Plasmid (h) - sc-404997 from Santa Cruz Biotechnology
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chordin HDR Plasmid (h) - sc-404997-HDR from Santa Cruz Biotechnology
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chordin Double Nickase Plasmid (h) - sc-404997-NIC from Santa Cruz Biotechnology
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chordin Double Nickase Plasmid (h2) - sc-404997-NIC-2 from Santa Cruz Biotechnology
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chordin CRISPR Activation Plasmid (h) - sc-404997-ACT from Santa Cruz Biotechnology
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chordin CRISPR Activation Plasmid (h2) - sc-404997-ACT-2 from Santa Cruz Biotechnology
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chordin Lentiviral Activation Particles (h) - sc-404997-LAC from Santa Cruz Biotechnology
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chordin Lentiviral Activation Particles (h2) - sc-404997-LAC-2 from Santa Cruz Biotechnology
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chordin siRNA (h) - sc-42136 from Santa Cruz Biotechnology
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chordin shRNA Plasmid (h) - sc-42136-SH from Santa Cruz Biotechnology
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chordin shRNA (h) Lentiviral Particles - sc-42136-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN6087 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6087 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03100 from Sigma-Aldrich
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CHRD siRNA (Human) - CRH5684 from Cohesion Biosciences
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CHRD - MBS8224312 from MyBioSource
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shRNA set against Human CHRD (NM_003741.2) - SHH263405 from Creative biogene
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shRNA set against Human CHRD(NM_003741.2) - SHG176865 from Creative biogene
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CHRD shRNA Plasmid (Human) - CHH5684 from Cohesion Biosciences
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CHRD miRNA 3'UTR clone - MiUTR1H-02132 from Creative biogene
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