Gene Symbol | SYTL4 |
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Entrez Gene | 94121 |
Alt Symbol | SLP4 |
Species | Human |
Gene Type | protein-coding |
Description | synaptotagmin-like 4 |
Other Description | exophilin-2|granuphilin-a|synaptotagmin-like protein 4 |
Swissprots | Q9H4R1 Q5H9J3 Q9H4R0 Q5JPG8 Q8N9P4 Q96C24 |
Accessions | CAI42004 CAI42005 EAX02813 EAX02814 EAX02815 Q96C24 AF302493 AAQ14492 AK098279 BAG53606 AK292588 BAF85277 AK313086 BAG35911 AL832596 CAI46126 BC014913 AAH14913 BP354718 BX537410 CAD97652 DB285556 XM_005262229 XP_005262286 XM_006724718 XP_006724781 XM_011531068 XP_011529370 NM_001129896 NP_001123368 NM_001174068 NP_001167539 NM_080737 NP_542775 |
Function | Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Detected close to the plasma membrane and on secretory granules. In pancreas, interacts with insulin-containing vesicles (By similarity). {ECO:0000250}. |
granuphilin CRISPR/Cas9 KO Plasmid (h) - sc-418220 from Santa Cruz Biotechnology
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granuphilin HDR Plasmid (h) - sc-418220-HDR from Santa Cruz Biotechnology
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granuphilin Double Nickase Plasmid (h) - sc-418220-NIC from Santa Cruz Biotechnology
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granuphilin Double Nickase Plasmid (h2) - sc-418220-NIC-2 from Santa Cruz Biotechnology
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granuphilin CRISPR Activation Plasmid (h) - sc-418220-ACT from Santa Cruz Biotechnology
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granuphilin CRISPR Activation Plasmid (h2) - sc-418220-ACT-2 from Santa Cruz Biotechnology
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granuphilin Lentiviral Activation Particles (h) - sc-418220-LAC from Santa Cruz Biotechnology
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granuphilin Lentiviral Activation Particles (h2) - sc-418220-LAC-2 from Santa Cruz Biotechnology
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granuphilin siRNA (h) - sc-45507 from Santa Cruz Biotechnology
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granuphilin shRNA Plasmid (h) - sc-45507-SH from Santa Cruz Biotechnology
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granuphilin shRNA (h) Lentiviral Particles - sc-45507-V from Santa Cruz Biotechnology
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SYTL4 RNAi - H00094121-R01 from Novus Biologicals
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MISSION® esiRNA - EHU072381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20933 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20933 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10099 from Sigma-Aldrich
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SYTL4 siRNA (Human) - CRJ4255 from Cohesion Biosciences
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SYTL4 - MBS827263 from MyBioSource
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shRNA set against Human SYTL4 (NM_080737.2) - SHH422152 from Creative biogene
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SYTL4 shRNA Plasmid (Human) - CHJ4255 from Cohesion Biosciences
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SYTL4 miRNA 3'UTR clone - MiUTR3H-02921 from Creative biogene
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SYTL4 miRNA 3'UTR clone - MiUTR3H-02922 from Creative biogene
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