| Gene Symbol |
SLC9A2
|
| Entrez Gene |
6549
|
| Alt Symbol |
NHE2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
|
| Other Description |
Na(+)/H(+) exchanger 2|sodium/hydrogen exchanger 2|solute carrier family 9 (sodium/hydrogen exchanger)|solute carrier family 9 (sodium/hydrogen exchanger), member 2|solute carrier family 9 member 2
|
| Swissprots |
B2RMS2 Q9UBY0
|
| Accessions |
AAF19248 AAK58694 EAX01788 EAX01789 Q9UBY0 AA843986 AF073299 AAD41635 AK129936 BC035787 BC136377 AAI36378 BC136378 AAI36379 S83549 AAB50820 NM_003048 NP_003039
|
| Function |
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.
|