Gene Symbol | RPS6KC1 |
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Entrez Gene | 26750 |
Alt Symbol | RPK118, RSKL1, S6K-delta-1, S6PKh1, humS6PKh1 |
Species | Human |
Gene Type | protein-coding |
Description | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
Other Description | 52 kDa ribosomal protein S6 kinase|SPHK1-binding protein|ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein|ribosomal protein S6 kinase delta-1 |
Swissprots | Q9UL66 Q96S38 B1APS8 Q9NSF4 Q8TDD3 D3DTA4 B3KVM4 |
Accessions | EAW93362 EAW93363 EAW93364 Q96S38 AB070706 BAB63956 AF037447 AAF13027 AF477978 AAL84818 AK122921 AK122989 BAG53836 AK295053 BAG58102 AK299298 BAG61312 AL356893 CAB92850 BC104769 AAI04770 BC143449 BC143473 BC143474 BX647303 DB060692 DC323473 EF491805 XM_005273095 XP_005273152 XM_005273096 XP_005273153 XM_006711272 XP_006711335 XM_011509411 XP_011507713 NM_001136138 NP_001129610 NM_001287218 NP_001274147 NM_001287219 NP_001274148 NM_001287220 NP_001274149 NM_001287221 NP_001274150 NM_012424 NP_036556 |
Function | May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12077123}. Membrane {ECO:0000269|PubMed:12077123}. Note=Also found in some small dot-like or ring-shaped early endosome structures. |
Tissue Specificity | Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon. {ECO:0000269|PubMed:12077123}. |
p52 S6 kinase CRISPR/Cas9 KO Plasmid (h) - sc-409890 from Santa Cruz Biotechnology
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p52 S6 kinase HDR Plasmid (h) - sc-409890-HDR from Santa Cruz Biotechnology
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p52 S6 kinase Double Nickase Plasmid (h) - sc-409890-NIC from Santa Cruz Biotechnology
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p52 S6 kinase Double Nickase Plasmid (h2) - sc-409890-NIC-2 from Santa Cruz Biotechnology
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p52 S6 kinase CRISPR Activation Plasmid (h) - sc-409890-ACT from Santa Cruz Biotechnology
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p52 S6 kinase CRISPR Activation Plasmid (h2) - sc-409890-ACT-2 from Santa Cruz Biotechnology
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p52 S6 kinase Lentiviral Activation Particles (h) - sc-409890-LAC from Santa Cruz Biotechnology
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p52 S6 kinase Lentiviral Activation Particles (h2) - sc-409890-LAC-2 from Santa Cruz Biotechnology
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p52 S6 kinase siRNA (h) - sc-88609 from Santa Cruz Biotechnology
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p52 S6 kinase shRNA Plasmid (h) - sc-88609-SH from Santa Cruz Biotechnology
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p52 S6 kinase shRNA (h) Lentiviral Particles - sc-88609-V from Santa Cruz Biotechnology
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RPS6KC1 RNAi - H00026750-R02 from Novus Biologicals
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MISSION® esiRNA - EHU045531 from Sigma-Aldrich
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MISSION® siRNA - SIHK2032 from Sigma-Aldrich
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MISSION® siRNA - SIHK2033 from Sigma-Aldrich
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MISSION® siRNA - SIHK2031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18658 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18658 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07345 from Sigma-Aldrich
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RPS6KC1 siRNA (Human) - CRH8896 from Cohesion Biosciences
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RPS6KC1 - MBS8225604 from MyBioSource
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Human RPS6KC1 siRNA - orb269398 from Biorbyt
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RPS6KC1 shRNA Plasmid (Human) - CHH8896 from Cohesion Biosciences
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RPS6KC1 miRNA 3'UTR clone - MiUTR3H-15958 from Creative biogene
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RPS6KC1 miRNA 3'UTR clone - MiUTR3H-15959 from Creative biogene
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