Gene Symbol |
Cyp51
|
Entrez Gene |
13121
|
Alt Symbol |
AI426508, CYPLI, Cyp51a1, Ldm, P450-14DM, P450LI
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
cytochrome P450, family 51
|
Other Description |
cytochrome P450 51A1|cytochrome P450, 51|cytochrome P450-14DM|cytochrome P45014DM|cytochrome P450LI|lanosterol 14-alpha demethylase|lanosterol 14-alpha-demethylase|sterol 14-alpha demethylase
|
Swissprots |
Q8BSQ7 Q9JIY3 Q8K0C4 Q9JIP8
|
Accessions |
AAF74562 EDL14627 Q8K0C4 AF166266 AAF73986 AK002827 BAB22388 AK028355 BAC25900 AK028815 BAC26134 AK031059 BAC27231 AK050781 AK075764 AK076983 BAC36548 AK179972 AK193495 AK202785 AK207015 AK208162 AK210661 AK217526 BC031813 AAH31813 CB524876 NM_020010 NP_064394
|
Function |
Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. {ECO:0000250}.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000305}. Microsome membrane {ECO:0000305}.
|
Top Pathways |
Steroid biosynthesis
|