| Gene Symbol |
GALNT10
|
| Entrez Gene |
55568
|
| Alt Symbol |
GALNACT10, PPGALNACT10, PPGANTASE10
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
polypeptide N-acetylgalactosaminyltransferase 10
|
| Other Description |
GalNAc transferase 10|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
|
| Swissprots |
Q8IXJ2 Q9Y4M4 Q8TEJ2 Q86SR1 B3KXC9 Q6IN56 Q86VP8 Q96IV2 Q9H8E1
|
| Accessions |
EAW61639 EAW61640 EAW61641 EAW61642 EAW61643 EAW61644 Q86SR1 AB078145 BAC56890 AF086521 AJ505950 CAD44532 AK023782 BAB14676 AK023815 AK024931 AK074132 BAB84958 AK127135 BAG54441 AL096739 CAB46378 BC007224 AAH07224 BC050333 BC072450 AAH72450 BC098444 AAH98444 BC148615 AAI48616 BC153181 AAI53182 BE875528 BG743249 BQ549377 BU661066 NM_198321 NP_938080 NM_017540 NM_024564
|
| Function |
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. Expressed at high level in small intestine, and at intermediate levels in stomach, pancreas, ovary, thyroid gland and spleen. Weakly expressed in other tissues. {ECO:0000269|PubMed:12417297}.
|
| Top Pathways |
Mucin type O-Glycan biosynthesis
|