Gene Symbol | PPP2R5D |
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Entrez Gene | 5528 |
Alt Symbol | B56D |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 2, regulatory subunit B', delta |
Other Description | PP2A B subunit isoform B'-delta|PP2A B subunit isoform B56-delta|PP2A B subunit isoform PR61-delta|PP2A B subunit isoform R5-delta|PP2A, B subunit, B' delta isoform|PP2A, B subunit, B56 delta isoform|PP2A, B subunit, PR61 delta isoform|PP2A, B subunit, R5 delta isoform|Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, delta isoform|protein phosphatase 2, regulatory subunit B (B56), delta isoform|protein phosphatase 2, regulatory subunit B', delta isoform|serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform |
Swissprots | Q15171 Q5TC39 B5BUA6 O00494 Q14738 O00696 A8K3I9 |
Accessions | EAX04130 EAX04131 EAX04132 EAX04133 EAX04134 Q14738 AB000634 BAA20381 AB000635 BAA20382 AB209861 BAD93098 AB451342 BAG70156 AB451357 BAG70171 AK122701 AK290604 BAF83293 AK291797 BAF84486 AK299696 BAG61599 BC001095 AAH01095 BC001175 AAH01175 BC010692 AAH10692 D78360 BAA11372 DA388594 EU446999 ABZ92528 L76702 AAB69751 NM_001270476 NP_001257405 NM_006245 NP_006236 NM_180976 NP_851307 NM_180977 NP_851308 |
Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
Subcellular Location | Cytoplasm. Nucleus. Note=Nuclear in interphase, nuclear during mitosis. |
Tissue Specificity | Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain. |
Top Pathways | Oocyte meiosis, mRNA surveillance pathway, Dopaminergic synapse, PI3K-Akt signaling pathway, Adrenergic signaling in cardiomyocytes |
PP2A-B56-δ siRNA (h) - sc-95565 from Santa Cruz Biotechnology
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PP2A-B56-δ shRNA Plasmid (h) - sc-95565-SH from Santa Cruz Biotechnology
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PP2A-B56-δ shRNA (h) Lentiviral Particles - sc-95565-V from Santa Cruz Biotechnology
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PPP2R5D RNAi - H00005528-R02 from Novus Biologicals
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PPP2R5D RNAi - H00005528-R01 from Novus Biologicals
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MISSION® esiRNA - EHU067721 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0645 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0643 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0644 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17302 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17302 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08302 from Sigma-Aldrich
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PPP2R5D siRNA (Human) - CRH3707 from Cohesion Biosciences
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PPP2R5D RNAi - H00005528-R03 from Novus Biologicals
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shRNA set against Human PPP2R5D (NM_006245.3) - SHH381508 from Creative biogene
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PPP2R5D shRNA Plasmid (Human) - CHH3707 from Cohesion Biosciences
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PPP2R5D miRNA 3'UTR clone - MiUTR3H-04283 from Creative biogene
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PPP2R5D miRNA 3'UTR clone - MiUTR3H-04284 from Creative biogene
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PPP2R5D miRNA 3'UTR clone - MiUTR3H-04285 from Creative biogene
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