Gene Symbol | ERAL1 |
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Entrez Gene | 26284 |
Alt Symbol | ERA, ERAL1A, H-ERA, HERA-A, HERA-B |
Species | Human |
Gene Type | protein-coding |
Description | Era-like 12S mitochondrial rRNA chaperone 1 |
Other Description | CEGA|ERA-W|ERA-like protein 1|Era G-protein-like 1|GTP-binding protein era homolog|GTPase Era, mitochondrial|GTPase, human homolog of E. coli essential cell cycle protein Era|conserved ERA-like GTPase|era (E. coli G-protein homolog)-like 1|hERA |
Swissprots | C9JEC6 O75617 Q96TC0 Q8WUY4 Q96LE2 B3KN21 O75616 |
Accessions | EAW51146 EAW51147 EAW51148 EAW51149 O75616 AB049388 BAB56112 AF082657 AAC31603 AF082658 AAC31604 AK023342 BAG51183 AY007435 AAG12978 BC019094 AAH19094 BX537542 DQ892626 ABM83552 DQ895866 ABM86792 NM_005702 NP_005693 |
Function | Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly. {ECO:0000269|PubMed:20430825, ECO:0000269|PubMed:20604745}. |
Subcellular Location | Mitochondrion matrix. Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes on the matrix side on the mitochondrial inner membrane. |
ERAL1 CRISPR/Cas9 KO Plasmid (h) - sc-408480 from Santa Cruz Biotechnology
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ERAL1 HDR Plasmid (h) - sc-408480-HDR from Santa Cruz Biotechnology
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ERAL1 Double Nickase Plasmid (h) - sc-408480-NIC from Santa Cruz Biotechnology
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ERAL1 Double Nickase Plasmid (h2) - sc-408480-NIC-2 from Santa Cruz Biotechnology
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ERAL1 CRISPR Activation Plasmid (h) - sc-408480-ACT from Santa Cruz Biotechnology
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ERAL1 CRISPR Activation Plasmid (h2) - sc-408480-ACT-2 from Santa Cruz Biotechnology
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ERAL1 Lentiviral Activation Particles (h) - sc-408480-LAC from Santa Cruz Biotechnology
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ERAL1 Lentiviral Activation Particles (h2) - sc-408480-LAC-2 from Santa Cruz Biotechnology
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ERAL1 siRNA (h) - sc-94130 from Santa Cruz Biotechnology
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ERAL1 shRNA Plasmid (h) - sc-94130-SH from Santa Cruz Biotechnology
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ERAL1 shRNA (h) Lentiviral Particles - sc-94130-V from Santa Cruz Biotechnology
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GTP binding protein era homolog RNAi - H00026284-R01 from Novus Biologicals
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MISSION® esiRNA - EHU131961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7942 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7942 from Sigma-Aldrich
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ERAL1 siRNA (Human) - CRH8804 from Cohesion Biosciences
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ERAL1 - MBS8225120 from MyBioSource
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shRNA set against Human ERAL1 (NM_005702.2) - SHH286765 from Creative biogene
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shRNA set against Human ERAL1(NM_005702.2) - SHH037523 from Creative biogene
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Human ERAL1 siRNA - orb269306 from Biorbyt
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ERAL1 shRNA Plasmid (Human) - CHH8804 from Cohesion Biosciences
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ERAL1 miRNA 3'UTR clone - MiUTR1H-03280 from Creative biogene
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