Gene Symbol | B4GALT6 |
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Entrez Gene | 9331 |
Alt Symbol | B4Gal-T6, beta4Gal-T6 |
Species | Human |
Gene Type | protein-coding |
Description | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 |
Other Description | UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6|UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase|UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6|beta-1,4-GalTase 6|beta-1,4-galactosyltransferase 6|beta4GalT-VI |
Swissprots | Q6NT09 O60514 Q9UBX8 |
Accessions | EAX01267 EAX01268 EAX01269 Q9UBX8 AB024742 BAA76273 AB209194 BAD92431 AF038664 AAC39737 AF069054 AAC21570 AF097159 AAD41695 AK314860 BAG37376 BC069620 AAH69620 BC069642 AAH69642 BC074835 AAH74835 BC074884 AAH74884 XM_005258387 XP_005258444 XM_006722578 XP_006722641 XM_006722579 XP_006722642 XM_011526262 XP_011524564 NM_004775 NP_004766 |
Function | Required for the biosynthesis of glycosphingolipids. {ECO:0000269|PubMed:1551920, ECO:0000269|PubMed:3099851}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack. |
Tissue Specificity | High expression in brain and adrenal gland, lower in liver, lung, colon and peripheral white blood cells. |
Top Pathways | Sphingolipid metabolism |
β-1,4-Gal-T6 siRNA (h) - sc-72406 from Santa Cruz Biotechnology
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β-1,4-Gal-T6 shRNA Plasmid (h) - sc-72406-SH from Santa Cruz Biotechnology
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β-1,4-Gal-T6 shRNA (h) Lentiviral Particles - sc-72406-V from Santa Cruz Biotechnology
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B4GALT6 RNAi - H00009331-R01 from Novus Biologicals
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MISSION® esiRNA - EHU082611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3824 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3824 from Sigma-Aldrich
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B4GALT6 siRNA (Human) - CRH6175 from Cohesion Biosciences
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B4GALT6 - MBS8209472 from MyBioSource
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shRNA set against Human B4GALT6 (NM_004775.3) - SHH244458 from Creative biogene
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B4GALT6 shRNA Plasmid (Human) - CHH6175 from Cohesion Biosciences
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B4GALT6 miRNA 3'UTR clone - MiUTR4H-TG00707 from Creative biogene
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