KCNJ5

Gene Symbol	KCNJ5
Entrez Gene	3762
Alt Symbol	CIR, GIRK4, KATP1, KIR3.4, LQT13
Species	Human
Gene Type	protein-coding
Description	potassium channel, inwardly rectifying subfamily J, member 5
Other Description	G protein-activated inward rectifier potassium channel 4|IRK-4|cardiac ATP-sensitive potassium channel|heart KATP channel|inward rectifier K+ channel KIR3.4|potassium inwardly-rectifying channel, subfamily J, member 5
Swissprots	Q6DK13 B2R744 Q6DK14 P48544 Q92807
Accessions	EAW67726 EAW67727 P48544 AB690268 BAL72885 AK312837 BAG35691 BC069386 AAH69386 BC069482 AAH69482 BC069499 AAH69499 BC069571 AAH69571 BC074838 AAH74838 BC074839 AAH74839 BC096834 AAH96834 BX647543 D50134 BAA08814 HQ447428 ADQ31914 JN859132 AFB82769 JN859133 AFB82770 L47208 AAB07269 U39195 AAB53093 X83582 CAA58565 XM_011542809 XP_011541111 XM_011542810 XP_011541112 NM_000890 NP_000881
Function	This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.
Subcellular Location	Membrane; Multi-pass membrane protein.
Tissue Specificity	Islets, exocrine pancreas and heart. Expressed in the adrenal cortex, particularly the zona glomerulosa. {ECO:0000269|PubMed:21311022}.
Top Pathways	Dopaminergic synapse, Morphine addiction, Retrograde endocannabinoid signaling, Circadian entrainment, Estrogen signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KCNJ5 protein fragment - ab158786 from Abcam Category Protein Source Wheat germ Species Human

CIR1 Antibody Blocking Peptide - LS-E11929 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CIR1 Antibody Blocking Peptide - LS-E11930 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CIR1 Antibody Blocking Peptide - LS-E13852 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNJ5 / Kir3.4 / GIRK4 Antibody Blocking Peptide - LS-E12475 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Kir3.4 Protein - H00003762-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

KCNJ5 Blocking Peptide - 33R-1190 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Kir3.4 Blocking Peptide - abx062842 from Abbexa Category Peptide Species Human, Mouse, Rat

KCNJ5 - H00003762-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

KCNJ5 - H00003762-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

KCNJ5 fusion protein - ag12656 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Potassium Inwardly Rectifying Channel Subfamily J, Member 5 (KCNJ5) - RPQ277Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Kir3.4 Blocking Peptide - CBP1648 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

KIR3.4 Peptide - BS5775P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

KCNJ5 Protein - abx164215 from Abbexa Category Protein Species Human, Mouse, Rat

KCNJ5 - TP310184 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Kir3.4 Recombinant Protein Antigen - NBP1-88081PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Kir3.4 Protein - NBP1-88082PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

KCNJ5 Peptide, Human - M34GP07971H from Creative Peptides Category Peptide Source Synthetic. Species Human

G protein-activated inward rectifier potassium channel 4 (KCNJ5), Recombinant Protein - MBS957904 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

G protein-activated inward rectifier potassium channel 4 (KCNJ5), Recombinant Protein - MBS7017707 from MyBioSource Category Protein Prices $1,225.00, $2,210.00, $3,415.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

KCNJ5 peptide - orb217511 from Biorbyt Category Peptide Species Human, Mouse, Rat

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