Gene Symbol | CDH4 |
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Entrez Gene | 1002 |
Alt Symbol | CAD4, R-CAD, RCAD |
Species | Human |
Gene Type | protein-coding |
Description | cadherin 4, type 1, R-cadherin (retinal) |
Other Description | R-cadherin|cadherin 4, type 1, preproprotein|cadherin-4|retinal cadherin |
Swissprots | B3KWB8 Q2M208 Q9BZ05 Q5VZ44 G3V1P8 P55283 |
Accessions | EAW75408 EAW75409 EAW75410 P55283 AA213385 AI422259 AK025855 BAB15259 AK091496 BAC03677 AK092092 AK124724 BAG54080 AK308345 AK315192 BAG37632 AL834206 CAD38893 BC101651 AAI01652 BC112150 AAI12151 BM664894 DC330816 L34059 AAA35627 NM_001252338 NP_001239267 NM_001252339 NP_001239268 NM_001794 NP_001785 |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed mainly in brain but also found in other tissues. |
Top Pathways | Cell adhesion molecules (CAMs) |
R-cadherin CRISPR/Cas9 KO Plasmid (h) - sc-418291 from Santa Cruz Biotechnology
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R-cadherin HDR Plasmid (h) - sc-418291-HDR from Santa Cruz Biotechnology
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R-cadherin Double Nickase Plasmid (h) - sc-418291-NIC from Santa Cruz Biotechnology
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R-cadherin Double Nickase Plasmid (h2) - sc-418291-NIC-2 from Santa Cruz Biotechnology
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R-cadherin CRISPR Activation Plasmid (h) - sc-418291-ACT from Santa Cruz Biotechnology
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R-cadherin CRISPR Activation Plasmid (h2) - sc-418291-ACT-2 from Santa Cruz Biotechnology
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R-cadherin Lentiviral Activation Particles (h) - sc-418291-LAC from Santa Cruz Biotechnology
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R-cadherin Lentiviral Activation Particles (h2) - sc-418291-LAC-2 from Santa Cruz Biotechnology
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R-cadherin siRNA (h) - sc-37039 from Santa Cruz Biotechnology
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R-cadherin shRNA Plasmid (h) - sc-37039-SH from Santa Cruz Biotechnology
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R-cadherin shRNA (h) Lentiviral Particles - sc-37039-V from Santa Cruz Biotechnology
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Cadherin-4/R-Cadherin RNAi - H00001002-R01 from Novus Biologicals
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MISSION® esiRNA - EHU075441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5822 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5822 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02378 from Sigma-Aldrich
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CDH4 siRNA (Human) - CRH0716 from Cohesion Biosciences
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CDH4 - MBS8228914 from MyBioSource
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shRNA set against Human CDH4 (NM_001794.3) - SHH260325 from Creative biogene
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CDH4 shRNA Plasmid (Human) - CHH0716 from Cohesion Biosciences
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CDH4 miRNA 3'UTR clone - MiUTR3H-05537 from Creative biogene
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