Gene Symbol | RECQL |
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Entrez Gene | 5965 |
Alt Symbol | RECQL1, RecQ1 |
Species | Human |
Gene Type | protein-coding |
Description | RecQ helicase-like |
Other Description | ATP-dependent DNA helicase Q1|DNA helicase, RecQ-like type 1|DNA-dependent ATPase Q1|RecQ protein-like (DNA helicase Q1-like)|recQ protein-like 1 |
Swissprots | A8K6G2 P46063 |
Accessions | EAW96434 EAW96435 EAW96436 EAW96437 EAW96438 P46063 AK291627 BAF84316 AV718094 AY157499 AAO61939 BC001052 AAH01052 BE794392 BT007119 AAP35783 CA431135 CN414472 CX784110 D37984 BAA07200 DA028052 DA547846 L36140 AAA60261 T94514 XM_005253461 XP_005253518 XM_005253462 XP_005253519 XM_005253463 XP_005253520 XM_005253464 XP_005253521 XM_006719133 XP_006719196 XM_011520811 XP_011519113 NM_002907 NP_002898 NM_032941 NP_116559 |
Function | DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. {ECO:0000269|PubMed:15886194, ECO:0000269|PubMed:7961977, ECO:0000269|PubMed:8056767}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:7961977}. |
Tissue Specificity | High expression in heart, lung, skeletal muscle and kidney, low expression in brain. {ECO:0000269|PubMed:7961977}. |
RecQL1 CRISPR/Cas9 KO Plasmid (h) - sc-402845 from Santa Cruz Biotechnology
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RecQL1 HDR Plasmid (h) - sc-402845-HDR from Santa Cruz Biotechnology
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RecQL1 Double Nickase Plasmid (h) - sc-402845-NIC from Santa Cruz Biotechnology
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RecQL1 Double Nickase Plasmid (h2) - sc-402845-NIC-2 from Santa Cruz Biotechnology
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RecQL1 CRISPR Activation Plasmid (h) - sc-402845-ACT from Santa Cruz Biotechnology
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RecQL1 CRISPR Activation Plasmid (h2) - sc-402845-ACT-2 from Santa Cruz Biotechnology
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RecQL1 Lentiviral Activation Particles (h) - sc-402845-LAC from Santa Cruz Biotechnology
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RecQL1 Lentiviral Activation Particles (h2) - sc-402845-LAC-2 from Santa Cruz Biotechnology
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RecQL1 siRNA (h) - sc-38217 from Santa Cruz Biotechnology
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RecQL1 shRNA Plasmid (h) - sc-38217-SH from Santa Cruz Biotechnology
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RecQL1 shRNA (h) Lentiviral Particles - sc-38217-V from Santa Cruz Biotechnology
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RECQ1 RNAi - H00005965-R04 from Novus Biologicals
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RECQ1 RNAi - H00005965-R03 from Novus Biologicals
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MISSION® esiRNA - EHU087561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18120 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18120 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03720 from Sigma-Aldrich
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RECQL siRNA (Human) - CRH4036 from Cohesion Biosciences
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RECQL - MBS827206 from MyBioSource
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shRNA set against Human RECQL (NM_002907.3) - SHH391600 from Creative biogene
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RecQL1 CRISPR/Cas9 KO Plasmid (h2) - sc-402845-KO-2 from Santa Cruz Biotechnology
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RecQL1 HDR Plasmid (h2) - sc-402845-HDR-2 from Santa Cruz Biotechnology
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Human RECQL siRNA - orb264538 from Biorbyt
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RECQL shRNA Plasmid (Human) - CHH4036 from Cohesion Biosciences
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RECQL miRNA 3'UTR clone - MiUTR3H-03458 from Creative biogene
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