Gene Symbol | PIGM |
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Entrez Gene | 93183 |
Alt Symbol | GPI-MT-I |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class M |
Other Description | DPM:GlcN-(acyl-)PI mannosyltransferase|GPI mannosyltransferase 1|GPI mannosyltransferase I|PIG-M mannosyltransferase|dol-P-Man dependent GPI mannosyltransferase|phosphatidylinositol-glycan biosynthesis class M protein |
Swissprots | Q9H3S5 |
Accessions | CAF86713 CAH05413 EAW52751 EAW52752 Q9H3S5 AB028127 BAB18567 AK074655 BAC11116 BC001803 AAH01803 BC011395 BC019865 AAH19865 BX643162 NM_145167 NP_660150 |
Function | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. {ECO:0000269|PubMed:11226175}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:11226175}; Multi-pass membrane protein {ECO:0000269|PubMed:11226175}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-M CRISPR/Cas9 KO Plasmid (h) - sc-413966 from Santa Cruz Biotechnology
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PIG-M HDR Plasmid (h) - sc-413966-HDR from Santa Cruz Biotechnology
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PIG-M Double Nickase Plasmid (h) - sc-413966-NIC from Santa Cruz Biotechnology
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PIG-M Double Nickase Plasmid (h2) - sc-413966-NIC-2 from Santa Cruz Biotechnology
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PIG-M CRISPR Activation Plasmid (h) - sc-413966-ACT from Santa Cruz Biotechnology
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PIG-M CRISPR Activation Plasmid (h2) - sc-413966-ACT-2 from Santa Cruz Biotechnology
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PIG-M Lentiviral Activation Particles (h) - sc-413966-LAC from Santa Cruz Biotechnology
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PIG-M Lentiviral Activation Particles (h2) - sc-413966-LAC-2 from Santa Cruz Biotechnology
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PIG-M siRNA (h) - sc-88676 from Santa Cruz Biotechnology
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PIG-M shRNA Plasmid (h) - sc-88676-SH from Santa Cruz Biotechnology
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PIG-M shRNA (h) Lentiviral Particles - sc-88676-V from Santa Cruz Biotechnology
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PIGM RNAi - H00093183-R01 from Novus Biologicals
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MISSION® esiRNA - EHU023711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16790 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16790 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11818 from Sigma-Aldrich
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PIGM siRNA (Human) - CRJ4195 from Cohesion Biosciences
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shRNA set against Human PIGM (NM_145167.2) - SHH375444 from Creative biogene
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shRNA set against Human PIGM(NM_145167.2) - SHR114178 from Creative biogene
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PIGM shRNA Plasmid (Human) - CHJ4195 from Cohesion Biosciences
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PIGM miRNA 3'UTR clone - MiUTR1H-07894 from Creative biogene
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