Gene Symbol | DRC7 |
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Entrez Gene | 84229 |
Alt Symbol | C16orf50, CCDC135, CFAP50, FAP50 |
Species | Human |
Gene Type | protein-coding |
Description | dynein regulatory complex subunit 7 |
Other Description | coiled-coil domain containing 135|coiled-coil domain-containing protein 135|coiled-coil domain-containing protein lobo homolog |
Swissprots | Q9H080 A8K943 Q8IY82 Q8NAA0 |
Accessions | EAW82947 EAW82948 EAW82949 Q8IY82 AK093035 BAC04026 AK093822 AK292558 BAF85247 AL136907 CAB66841 BC030661 BC036667 AAH36667 DB093780 DB095284 XM_011523377 XP_011521679 XM_011523378 XP_011521680 NM_001289162 NP_001276091 NM_001289163 NP_001276092 NM_032269 NP_115645 |
Function | Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility. {ECO:0000250|UniProtKB:A8JAM0}. |
Subcellular Location | Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:A8JAM0}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:A8JAM0}. Note=Associated with the outer doublet microtubules (OD). {ECO:0000250|UniProtKB:A8JAM0}. |
CCDC135 CRISPR/Cas9 KO Plasmid (h) - sc-413583 from Santa Cruz Biotechnology
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CCDC135 HDR Plasmid (h) - sc-413583-HDR from Santa Cruz Biotechnology
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CCDC135 Double Nickase Plasmid (h) - sc-413583-NIC from Santa Cruz Biotechnology
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CCDC135 Double Nickase Plasmid (h2) - sc-413583-NIC-2 from Santa Cruz Biotechnology
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CCDC135 CRISPR Activation Plasmid (h) - sc-413583-ACT from Santa Cruz Biotechnology
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CCDC135 CRISPR Activation Plasmid (h2) - sc-413583-ACT-2 from Santa Cruz Biotechnology
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CCDC135 Lentiviral Activation Particles (h) - sc-413583-LAC from Santa Cruz Biotechnology
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CCDC135 Lentiviral Activation Particles (h2) - sc-413583-LAC-2 from Santa Cruz Biotechnology
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CCDC135 siRNA (h) - sc-93485 from Santa Cruz Biotechnology
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CCDC135 shRNA Plasmid (h) - sc-93485-SH from Santa Cruz Biotechnology
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CCDC135 shRNA (h) Lentiviral Particles - sc-93485-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU151661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5478 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5478 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01335 from Sigma-Aldrich
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CCDC135 siRNA (Human) - CRJ3364 from Cohesion Biosciences
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CCDC135 - MBS8236858 from MyBioSource
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shRNA set against Human CCDC135 (NM_032269.5) - SHH256081 from Creative biogene
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Human CCDC135 siRNA - orb273865 from Biorbyt
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CCDC135 shRNA Plasmid (Human) - CHJ3364 from Cohesion Biosciences
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CCDC135 miRNA 3'UTR clone - MiUTR4H-TG01776 from Creative biogene
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