| Gene Symbol |
SLC30A7
|
| Entrez Gene |
148867
|
| Alt Symbol |
ZNT7, ZnT-7, ZnTL2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 30 (zinc transporter), member 7
|
| Other Description |
solute carrier family 30 member 7|zinc transporter 7|zinc transporter ZnT-7|zinc transporter like 2|znt-like transporter 2
|
| Swissprots |
B2R949 Q8TCH2 Q8NEW0 D3DT61
|
| Accessions |
CAD58286 EAW72942 EAW72943 Q8NEW0 AF233345 AAL83716 AF529197 AAO17324 AK023089 AK313638 BAG36396 AM392927 CAL37805 AY094606 AAM21969 BC064692 AAH64692 BX537375 CAD97617 BX648884 CR936806 DA997188 HG492323 XM_011540779 XP_011539081 XR_246237 NM_001144884 NP_001138356 NM_133496 NP_598003
|
| Function |
Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:12446736}; Multi-pass membrane protein {ECO:0000269|PubMed:12446736}.
|