| Gene Symbol |
TCF20
|
| Entrez Gene |
6942
|
| Alt Symbol |
AR1, SPBP, TCF-20
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transcription factor 20 (AR1)
|
| Other Description |
SPRE-binding protein|nuclear factor SPBP|stromelysin-1 PDGF-responsive element-binding protein|stromelysin-1 platelet-derived growth factor-responsive element binding protein|transcription factor 20
|
| Swissprots |
Q13078 Q9UGU0 O14528 Q9H4M0 Q4V353 A9JX12
|
| Accessions |
AAG28930 EAW60495 EAW60496 EAW60497 EAW60498 Q9UGU0 AB006630 BAA22961 BC013180 BC156502 AAI56503 BC172542 AAI72542 BU732753 KF851355 AHI43789 U19345 AAC36392 XM_005261722 XP_005261779 XM_006724313 XP_006724376 XM_011530352 XP_011528654 XM_011530353 XP_011528655 XM_011530354 XP_011528656 XM_011530355 XP_011528657 XM_011547035 XP_011545337 XM_011547036 XP_011545338 XM_011547752 XP_011546054 XM_011547753 XP_011546055 XM_011548817 XP_011547119 XM_011548818 XP_011547120 XM_011548820 XP_011547122 XM_011548821 XP_011547123 NM_005650 NP_005641 NM_181492 NP_852469
|
| Function |
Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Expressed in most tissues, except in ovary and prostate. Isoform 1 is exclusively expressed in brain, heart and testis, and this form predominates in liver and kidney. Isoform 2 predominates in lung.
|