Gene Symbol | PTGES |
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Entrez Gene | 9536 |
Alt Symbol | MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1 |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin E synthase |
Other Description | MGST1-like 1|glutathione S-transferase 1-like 1|microsomal glutathione S-transferase 1-like 1|microsomal prostaglandin E synthase 1|microsomal prostaglandin E synthase-1|p53-induced apoptosis protein 12|p53-induced gene 12 protein|tumor protein p53 inducible protein 12 |
Swissprots | O14900 O14684 Q5SZC0 |
Accessions | ABQ01233 CAB72099 O14684 AF010316 AAC39534 AF027740 AAB82299 AF217965 AAG17208 AF217972 AAG17215 AK127663 AK311947 BAG34888 BC008280 AAH08280 BC018201 BM550187 BQ927197 BX357872 BX396892 CB960064 XM_011519210 XP_011517512 NM_004878 NP_004869 NM_198797 |
Function | Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). {ECO:0000269|PubMed:18682561}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:18682561}; Multi-pass membrane protein {ECO:0000269|PubMed:18682561}. |
Top Pathways | Arachidonic acid metabolism |
PGE synthase CRISPR/Cas9 KO Plasmid (h) - sc-402085 from Santa Cruz Biotechnology
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PGE synthase HDR Plasmid (h) - sc-402085-HDR from Santa Cruz Biotechnology
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PGE synthase Double Nickase Plasmid (h) - sc-402085-NIC from Santa Cruz Biotechnology
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PGE synthase Double Nickase Plasmid (h2) - sc-402085-NIC-2 from Santa Cruz Biotechnology
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PGE synthase CRISPR Activation Plasmid (h) - sc-402085-ACT from Santa Cruz Biotechnology
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PGE synthase CRISPR Activation Plasmid (h2) - sc-402085-ACT-2 from Santa Cruz Biotechnology
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PGE synthase Lentiviral Activation Particles (h) - sc-402085-LAC from Santa Cruz Biotechnology
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PGE synthase Lentiviral Activation Particles (h2) - sc-402085-LAC-2 from Santa Cruz Biotechnology
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PGE synthase siRNA (h) - sc-41642 from Santa Cruz Biotechnology
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PGE synthase shRNA Plasmid (h) - sc-41642-SH from Santa Cruz Biotechnology
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PGE synthase shRNA (h) Lentiviral Particles - sc-41642-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN17668 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17668 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08604 from Sigma-Aldrich
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PTGES siRNA (Human) - CRH6341 from Cohesion Biosciences
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shRNA set against Human PTGES (NM_004878.4) - SHH386024 from Creative biogene
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Human Prostaglandin E synthase siRNA - orb266843 from Biorbyt
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PTGES shRNA Plasmid (Human) - CHH6341 from Cohesion Biosciences
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PTGES miRNA 3'UTR clone - MiUTR3H-07434 from Creative biogene
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