Gene Symbol | RDH14 |
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Entrez Gene | 57665 |
Alt Symbol | PAN2, SDR7C4 |
Species | Human |
Gene Type | protein-coding |
Description | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
Other Description | alcohol dehydrogenase PAN2|pancreas protein 2|retinol dehydrogenase 14|retinol dehydrogenase 14 (all-trans and 9-cis)|short chain dehydrogenase/reductase family 7C member 4|short chain dehydrogenase/reductase family 7C, member 4 |
Swissprots | Q9HBH5 |
Accessions | AAX93259 EAX00855 EAX00856 EAX00857 EAX00858 Q9HBH5 AF237952 AAG12190 AK023625 AK314994 BAG37490 AM393225 CAL38103 AY358511 AAQ88875 BC009830 AAH09830 BI546337 CD676669 NM_020905 NP_065956 |
Function | Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected. {ECO:0000269|PubMed:12226107}. |
Tissue Specificity | Expressed in brain, kidney, pancreas and placenta. |
RDH14 CRISPR/Cas9 KO Plasmid (h) - sc-412870 from Santa Cruz Biotechnology
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RDH14 HDR Plasmid (h) - sc-412870-HDR from Santa Cruz Biotechnology
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RDH14 Double Nickase Plasmid (h) - sc-412870-NIC from Santa Cruz Biotechnology
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RDH14 Double Nickase Plasmid (h2) - sc-412870-NIC-2 from Santa Cruz Biotechnology
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RDH14 CRISPR Activation Plasmid (h) - sc-412870-ACT from Santa Cruz Biotechnology
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RDH14 CRISPR Activation Plasmid (h2) - sc-412870-ACT-2 from Santa Cruz Biotechnology
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RDH14 Lentiviral Activation Particles (h) - sc-412870-LAC from Santa Cruz Biotechnology
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RDH14 Lentiviral Activation Particles (h2) - sc-412870-LAC-2 from Santa Cruz Biotechnology
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RDH14 siRNA (h) - sc-94559 from Santa Cruz Biotechnology
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RDH14 shRNA Plasmid (h) - sc-94559-SH from Santa Cruz Biotechnology
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RDH14 shRNA (h) Lentiviral Particles - sc-94559-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN18113 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18113 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04177 from Sigma-Aldrich
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RDH14 siRNA (Human) - CRJ1618 from Cohesion Biosciences
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RDH14 - MBS8225641 from MyBioSource
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shRNA set against Human RDH14 (NM_020905.3) - SHH391488 from Creative biogene
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Human RDH14 siRNA - orb272119 from Biorbyt
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RDH14 shRNA Plasmid (Human) - CHJ1618 from Cohesion Biosciences
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RDH14 miRNA 3'UTR clone - MiUTR3H-15613 from Creative biogene
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