Gene Symbol | CDC42EP4 |
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Entrez Gene | 23580 |
Alt Symbol | BORG4, CEP4, KAIA1777 |
Species | Human |
Gene Type | protein-coding |
Description | CDC42 effector protein (Rho GTPase binding) 4 |
Other Description | binder of Rho GTPases 4|cdc42 effector protein 4 |
Swissprots | Q9H3Q1 O95828 B3KUS7 Q96FT3 |
Accessions | CAC40577 CAE91451 EAW89123 EAW89124 Q9H3Q1 AB042237 BAB17272 AF099664 AAD16299 AK027385 BAG51313 AK097835 BAG53539 AK312536 BAG35435 AL162074 BC002774 AAH02774 BC010451 AAH10451 BE387060 BI560730 HQ447559 ADQ32045 XM_005257182 XP_005257239 NM_012121 NP_036253 |
Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts. |
Subcellular Location | Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton. |
Tissue Specificity | Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues. |
Cdc42EP4 CRISPR/Cas9 KO Plasmid (h) - sc-408523 from Santa Cruz Biotechnology
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Cdc42EP4 HDR Plasmid (h) - sc-408523-HDR from Santa Cruz Biotechnology
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Cdc42EP4 Double Nickase Plasmid (h) - sc-408523-NIC from Santa Cruz Biotechnology
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Cdc42EP4 Double Nickase Plasmid (h2) - sc-408523-NIC-2 from Santa Cruz Biotechnology
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Cdc42EP4 CRISPR Activation Plasmid (h) - sc-408523-ACT from Santa Cruz Biotechnology
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Cdc42EP4 CRISPR Activation Plasmid (h2) - sc-408523-ACT-2 from Santa Cruz Biotechnology
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Cdc42EP4 Lentiviral Activation Particles (h) - sc-408523-LAC from Santa Cruz Biotechnology
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Cdc42EP4 Lentiviral Activation Particles (h2) - sc-408523-LAC-2 from Santa Cruz Biotechnology
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Cdc42EP4 siRNA (h) - sc-94218 from Santa Cruz Biotechnology
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Cdc42EP4 shRNA Plasmid (h) - sc-94218-SH from Santa Cruz Biotechnology
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Cdc42EP4 shRNA (h) Lentiviral Particles - sc-94218-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU133751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5789 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5789 from Sigma-Aldrich
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CDC42EP4 siRNA (Human) - CRH8371 from Cohesion Biosciences
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CDC42EP4 - MBS8239103 from MyBioSource
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shRNA set against Human CDC42EP4(NM_012121.4) - SHG161881 from Creative biogene
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CDC42EP4 shRNA Plasmid (Human) - CHH8371 from Cohesion Biosciences
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CDC42EP4 miRNA 3'UTR clone - MiUTR1H-01960 from Creative biogene
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