Gene Symbol | AMZ2 |
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Entrez Gene | 51321 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | archaelysin family metallopeptidase 2 |
Other Description | archaemetzincin-2|archaemetzincins-2|archeobacterial metalloproteinase-like protein 2 |
Swissprots | Q5XKF1 A6NLD9 Q86W34 B3KR44 Q9NZE2 |
Accessions | EAW89047 EAW89048 EAW89049 EAW89050 EAW89051 Q86W34 AJ635358 CAG25750 AK090981 BAG52256 AK126146 BAC86462 AW028610 BC035935 BC050709 AAH50709 BC056271 AAH56271 BE543044 BF978559 BM450564 BQ432895 CN278872 CN278874 HQ448615 ADQ33093 XM_005257432 XP_005257489 XM_005257433 XP_005257490 XM_005257435 XP_005257492 XM_005257436 XP_005257493 XM_005257437 XP_005257494 XM_005257438 XP_005257495 XM_006721940 XP_006722003 NM_001033569 NP_001028741 NM_001033570 NP_001028742 NM_001033571 NP_001028743 NM_001033572 NP_001028744 NM_001033574 NP_001028746 NM_001289054 NP_001275983 NM_001289056 NP_001275985 NM_016627 NP_057711 |
Function | Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2. {ECO:0000269|PubMed:15972818}. |
Tissue Specificity | Predominantly expressed in heart and testis. Also expressed at lower levels in kidney, liver, pancreas, lung, brain and placenta. Expressed in fetal tissues such as kidney, liver, lung and brain. Down-regulated in testis from patients with maturation arrest (MA) or Sertoli cell-only syndrome (SCOS). {ECO:0000269|PubMed:15972818, ECO:0000269|PubMed:17074343}. |
AMZ2 CRISPR/Cas9 KO Plasmid (h) - sc-412183 from Santa Cruz Biotechnology
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AMZ2 HDR Plasmid (h) - sc-412183-HDR from Santa Cruz Biotechnology
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AMZ2 Double Nickase Plasmid (h) - sc-412183-NIC from Santa Cruz Biotechnology
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AMZ2 Double Nickase Plasmid (h2) - sc-412183-NIC-2 from Santa Cruz Biotechnology
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AMZ2 CRISPR Activation Plasmid (h) - sc-412183-ACT from Santa Cruz Biotechnology
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AMZ2 CRISPR Activation Plasmid (h2) - sc-412183-ACT-2 from Santa Cruz Biotechnology
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AMZ2 Lentiviral Activation Particles (h) - sc-412183-LAC from Santa Cruz Biotechnology
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AMZ2 Lentiviral Activation Particles (h2) - sc-412183-LAC-2 from Santa Cruz Biotechnology
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AMZ2 siRNA (h) - sc-94228 from Santa Cruz Biotechnology
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AMZ2 shRNA Plasmid (h) - sc-94228-SH from Santa Cruz Biotechnology
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AMZ2 shRNA (h) Lentiviral Particles - sc-94228-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU113341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3133 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3133 from Sigma-Aldrich
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AMZ2 siRNA (Human) - CRH9698 from Cohesion Biosciences
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AMZ2 - MBS8226020 from MyBioSource
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shRNA set against Human AMZ2 (NM_016627.4) - SHH236046 from Creative biogene
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shRNA set against Human AMZ2(NM_001033574.1) - SHG057115 from Creative biogene
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shRNA set against Human AMZ2(NM_001033569.1) - SHG057133 from Creative biogene
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Human AMZ2 siRNA - orb270200 from Biorbyt
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AMZ2 shRNA Plasmid (Human) - CHH9698 from Cohesion Biosciences
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AMZ2 miRNA 3'UTR clone - MiUTR1H-00352 from Creative biogene
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AMZ2 miRNA 3'UTR clone - MiUTR1H-00353 from Creative biogene
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AMZ2 miRNA 3'UTR clone - MiUTR3H-13565 from Creative biogene
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AMZ2 miRNA 3'UTR clone - MiUTR3H-13566 from Creative biogene
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