Gene Symbol | NDUFA2 |
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Entrez Gene | 4695 |
Alt Symbol | B8, CD14, CIB8 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2|NADH-ubiquinone oxidoreductase subunit CI-B8|complex I B8 subunit |
Swissprots | Q6IAY8 O43678 D6RJD6 |
Accessions | BAB21453 EAW62031 O43678 AA993683 AF047185 AAC04270 AF077029 AAD27762 BC003674 AAH03674 BM706616 BQ054127 CR457016 CAG33297 NM_001185012 NP_001171941 NM_002488 NP_002479 NR_033697 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFA2 CRISPR/Cas9 KO Plasmid (h) - sc-410897 from Santa Cruz Biotechnology
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NDUFA2 HDR Plasmid (h) - sc-410897-HDR from Santa Cruz Biotechnology
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NDUFA2 Double Nickase Plasmid (h) - sc-410897-NIC from Santa Cruz Biotechnology
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NDUFA2 Double Nickase Plasmid (h2) - sc-410897-NIC-2 from Santa Cruz Biotechnology
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NDUFA2 CRISPR Activation Plasmid (h) - sc-410897-ACT from Santa Cruz Biotechnology
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NDUFA2 CRISPR Activation Plasmid (h2) - sc-410897-ACT-2 from Santa Cruz Biotechnology
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NDUFA2 Lentiviral Activation Particles (h) - sc-410897-LAC from Santa Cruz Biotechnology
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NDUFA2 Lentiviral Activation Particles (h2) - sc-410897-LAC-2 from Santa Cruz Biotechnology
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NDUFA2 siRNA (h) - sc-92061 from Santa Cruz Biotechnology
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NDUFA2 shRNA Plasmid (h) - sc-92061-SH from Santa Cruz Biotechnology
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NDUFA2 shRNA (h) Lentiviral Particles - sc-92061-V from Santa Cruz Biotechnology
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NDUFA2 RNAi - H00004695-R01 from Novus Biologicals
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MISSION® esiRNA - EHU027291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15139 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15139 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01149 from Sigma-Aldrich
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NDUFA2 siRNA (Human) - CRH3110 from Cohesion Biosciences
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shRNA set against Human NDUFA2 (NM_002488.4) - SHH350520 from Creative biogene
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Human NDUFA2 siRNA - orb263612 from Biorbyt
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NDUFA2 shRNA Plasmid (Human) - CHH3110 from Cohesion Biosciences
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NDUFA2 miRNA 3'UTR clone - MiUTR3H-04700 from Creative biogene
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