Gene Symbol | TMEM237 |
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Entrez Gene | 65062 |
Alt Symbol | ALS2CR4, JBTS14 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 237 |
Other Description | amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein |
Swissprots | Q8IZ18 E9PBF8 Q53TS9 Q7Z3B6 Q53TT2 Q8NBF8 E9PAR8 Q96Q45 E9PG24 E9PGX0 Q96CY1 B4E2R8 B4E1R8 |
Accessions | AAY14694 AAY15056 EAW70281 EAW70282 EAW70283 EAW70284 Q96Q45 AB053301 BAB69011 AF212043 AAL56640 AK022836 AK090601 BAC03487 AK125841 AK303954 BAG64880 AK304395 BAG65230 BC013730 AAH13730 BC029611 AAH29611 BP226834 BQ219059 BX538000 CAD97955 JF432141 ADZ15358 NM_001044385 NP_001037850 NM_152388 NP_689601 |
Function | Component of the transition zone in primary cilia. Required for ciliogenesis. {ECO:0000269|PubMed:22152675}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell projection, cilium {ECO:0000269|PubMed:22152675}. Note=Localizes at the proximal region of primary cilia were observed, consistent with localization to the transition zone. Anchored to the transition zone by RPGRIP1L. |
ALS2CR4 CRISPR/Cas9 KO Plasmid (h) - sc-413072 from Santa Cruz Biotechnology
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ALS2CR4 HDR Plasmid (h) - sc-413072-HDR from Santa Cruz Biotechnology
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ALS2CR4 Double Nickase Plasmid (h) - sc-413072-NIC from Santa Cruz Biotechnology
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ALS2CR4 Double Nickase Plasmid (h2) - sc-413072-NIC-2 from Santa Cruz Biotechnology
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ALS2CR4 CRISPR Activation Plasmid (h) - sc-413072-ACT from Santa Cruz Biotechnology
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ALS2CR4 CRISPR Activation Plasmid (h2) - sc-413072-ACT-2 from Santa Cruz Biotechnology
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ALS2CR4 Lentiviral Activation Particles (h) - sc-413072-LAC from Santa Cruz Biotechnology
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ALS2CR4 Lentiviral Activation Particles (h2) - sc-413072-LAC-2 from Santa Cruz Biotechnology
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ALS2CR4 siRNA (h) - sc-95044 from Santa Cruz Biotechnology
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ALS2CR4 shRNA Plasmid (h) - sc-95044-SH from Santa Cruz Biotechnology
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ALS2CR4 shRNA (h) Lentiviral Particles - sc-95044-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU035731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3093 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3093 from Sigma-Aldrich
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TMEM237 siRNA (Human) - CRJ2172 from Cohesion Biosciences
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TMEM237 - MBS8221329 from MyBioSource
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shRNA set against Human TMEM237 (NM_152388.3) - SHH430336 from Creative biogene
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Human TMEM237 siRNA - orb272673 from Biorbyt
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TMEM237 shRNA Plasmid (Human) - CHJ2172 from Cohesion Biosciences
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TMEM237 miRNA 3'UTR clone - MiUTR4H-TG10539 from Creative biogene
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