Gene Symbol | HMG20B |
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Entrez Gene | 10362 |
Alt Symbol | BRAF25, BRAF35, HMGX2, HMGXB2, PP7706, SMARCE1r, SOXL, pp8857 |
Species | Human |
Gene Type | protein-coding |
Description | high mobility group 20B |
Other Description | BRCA2-associated factor 35|HMG box domain containing 2|HMG box-containing protein 20B|HMG domain-containing protein 2|HMG domain-containing protein HMGX2|SMARCE1-related protein|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1-related|Sox-like transcriptional factor|high-mobility group 20B|structural DNA-binding protein BRAF35 |
Swissprots | Q9P0W2 Q8NBD5 A6NMS5 Q9Y491 D6W616 Q9Y4A2 Q6IBP8 Q9HD21 |
Accessions | AAC62837 EAW69306 EAW69307 EAW69308 Q9P0W2 AF072165 AAF76253 AF072836 AAC26860 AF146223 AAF66707 AF288679 AAG01174 AF318366 AAL55873 AF331191 AAG60060 AK090733 BAC03510 AK129638 AK289500 BAF82189 AK310601 AK314201 AL355691 AL355702 AL355703 AL355709 CAB90809 BC002552 AAH02552 BC003505 AAH03505 BC004408 AAH04408 BC021585 AAH21585 BC134413 AAI34414 BI561304 CR456754 CAG33035 EU446934 ABZ92463 NM_006339 NP_006330 |
Function | Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters. |
Subcellular Location | Nucleus. Chromosome. Note=Localized to condensed chromosomes in mitosis in conjunction with BRCA2. |
Tissue Specificity | Ubiquitously expressed in adult tissues. {ECO:0000269|PubMed:10773667, ECO:0000269|PubMed:11997092}. |
BRAF35 CRISPR/Cas9 KO Plasmid (h) - sc-407940 from Santa Cruz Biotechnology
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BRAF35 HDR Plasmid (h) - sc-407940-HDR from Santa Cruz Biotechnology
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BRAF35 Double Nickase Plasmid (h) - sc-407940-NIC from Santa Cruz Biotechnology
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BRAF35 Double Nickase Plasmid (h2) - sc-407940-NIC-2 from Santa Cruz Biotechnology
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BRAF35 CRISPR Activation Plasmid (h) - sc-407940-ACT from Santa Cruz Biotechnology
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BRAF35 CRISPR Activation Plasmid (h2) - sc-407940-ACT-2 from Santa Cruz Biotechnology
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BRAF35 Lentiviral Activation Particles (h) - sc-407940-LAC from Santa Cruz Biotechnology
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BRAF35 Lentiviral Activation Particles (h2) - sc-407940-LAC-2 from Santa Cruz Biotechnology
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BRAF35 siRNA (h) - sc-37536 from Santa Cruz Biotechnology
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BRAF35 shRNA Plasmid (h) - sc-37536-SH from Santa Cruz Biotechnology
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BRAF35 shRNA (h) Lentiviral Particles - sc-37536-V from Santa Cruz Biotechnology
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BRAF35 RNAi - H00010362-R01 from Novus Biologicals
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MISSION® esiRNA - EHU090751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10157 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10157 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04011 from Sigma-Aldrich
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HMG20B siRNA (Human) - CRH7021 from Cohesion Biosciences
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HMG20B - MBS828118 from MyBioSource
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shRNA set against Human HMG20B (NM_006339.2) - SHH313249 from Creative biogene
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Human HMG20B siRNA - orb267523 from Biorbyt
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HMG20B shRNA Plasmid (Human) - CHH7021 from Cohesion Biosciences
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HMG20B miRNA 3'UTR clone - MiUTR1H-04600 from Creative biogene
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