| Gene Symbol |
HIST2H2BE
|
| Entrez Gene |
8349
|
| Alt Symbol |
GL105, H2B, H2B.1, H2BFQ, H2BGL105, H2BQ
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 2, H2be
|
| Other Description |
H2B histone family, member Q|histone 2, H2be|histone H2B type 2-E|histone H2B-GL105|histone H2B.q
|
| Swissprots |
Q16778 Q4KMY1 A8K110 Q9UE88 Q5QNX0 A3KMC7
|
| Accessions |
AAN59961 CAA41051 CAI12568 EAW53605 Q16778 AK093747 AK289725 BAF82414 BC005827 AAH05827 BC069193 AAH69193 BC096121 AAH96121 BC098112 AAH98112 BC098289 AAH98289 BC107084 AAI07085 BC107085 AAI07086 CR541895 CAG46693 HQ447538 ADQ32024 M60756 AAA63192 NM_003528 NP_003519
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism
|
![Western Blot: H2B Overexpression Lysate (Adult Normal) [NBL1-11571] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for H2B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5580_H2B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11571-img0002.jpg)