Gene Symbol | Tyrobp |
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Entrez Gene | 22177 |
Alt Symbol | DAP12, KARAP, Ly83 |
Species | Mouse |
Gene Type | protein-coding |
Description | TYRO protein tyrosine kinase binding protein |
Other Description | DNAX-activation protein 12|KAR-associated protein|TYRO protein tyrosine kinase-binding protein|killer cell activating receptor associated protein|killer-activating receptor-associated protein |
Swissprots | O54885 O88603 |
Accessions | EDL24026 EDL24027 O54885 AF024637 AAD09438 AF077829 AAC95529 AK154480 BAE32616 BC056450 AAH56450 NM_011662 NP_035792 |
Function | Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin. {ECO:0000269|PubMed:17086186}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Natural killer cell mediated cytotoxicity, Osteoclast differentiation |
DAP12 (A-20) - sc-7855 from Santa Cruz Biotechnology
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Anti -DAP12 (KARAP) - D1049-06C from USBiological Life Science
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DAP12 antibody - 70R-12373 from Fitzgerald
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TYROBP / DAP12 antibody - PAB9577 from Acris Antibodies
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Rabbit Anti-DAP12 Antibody - 168-10993 from RayBiotech
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Anti-TYROBP polyclonal antibody - DPAB-DC969 from Creative Diagnostics
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DAP12, Polyclonal Antibody - MBS395757 from MyBioSource
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DAP12 Antibody - 5570R-100 from Biovision
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DAP12, Polyclonal Antibody - MBS840274 from MyBioSource
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DAP12-Antibody - ABV11003 from Abgent, a WuXi AppTec company
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DAP12 Antibody - 5570R-30T from Biovision
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DAP12 Antibody - 5570R from Biovision
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