CR1

Gene Symbol CR1
Entrez Gene 1378
Alt Symbol C3BR, C4BR, CD35, KN
Species Human
Gene Type protein-coding
Description complement component (3b/4b) receptor 1 (Knops blood group)
Other Description C3-binding protein|C3b/C4b receptor|CD35 antigen|Knops blood group antigen|complement receptor type 1
Swissprots Q5SR45 Q16744 Q16745 P17927 Q5SR43 Q9UQV2
Accessions AAB60694 AAB60695 AAD15289 AAG09139 AAG09140 AAG14442 AAG14443 AAV65566 AAV65567 AAV65568 AAV65569 AAV65570 AAV65571 AAV65572 AAV65573 AAV65574 AAV65575 AAV65576 AAV65577 CAA32538 CAA32540 CAE82047 CDK60404 EAW93480 P17927 AK298486 BAG60695 AK309342 BC032550 BF900429 BX113709 BX643705 M11569 AAA52297 M11617 AAA52298 M11618 AAA52299 X05309 CAA28933 X14362 CAA32541 Y00816 CAA68755 XM_006711166 XP_006711229 XM_011509205 XP_011507507 NM_000573 NP_000564 NM_000651 NP_000642
Function Mediates cellular binding of particles and immune complexes that have activated complement.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells.
Top Pathways Complement and coagulation cascades, Hematopoietic cell lineage, Leishmaniasis, Malaria, Tuberculosis

CD35 (H-300) - sc-20924 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD35 (H-300): sc-20924. Western blot analysis of CD35 expression in TF-1 whole cell lysate.

CD35 (E-11) - sc-7308 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD35 (E-11) FITC: sc-7308 FITC. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2855.

CD35 (Ber-MAC-DRC) - sc-19662 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD35 (Ber-MAC-DRC): sc-19662. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human tonsil tissue showing membrane staining.

CD35 (N-19) - sc-7640 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD35 (N-19): sc-7640. Western blot analysis of CD35 expression in human PBL whole cell lysate.

CD35 (To5) - sc-20055 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD35 (To5) PE: sc-20055 PE. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

CD35 (H-2) - sc-166329 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD35 (H-2): sc-166329. Western blot analysis of CD35 expression in TF-1 whole cell lysate.

CD35 (J3D3) - sc-59022 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD35 (J3D3): sc-59022. Western blot analysis of CD35 expression in TF-1 whole cell lysate.

Anti-CD35 antibody [Ber-MAC DRC] - ab16720 from Abcam

Prices $370.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone Ber-MAC DRC

Anti-CD35 antibody [E11] - ab25 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone E11
ab25 (1µg/ml) staining CD35 in human spleen.Sections were stained using an automated system (DAKO Autostainer Plus ), at room temperature: sections were rehydrated and antigen retrieved with the Dako 3 in 1 AR buffers citrate pH6.1. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 mins. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS) then incubated with primary antibody for 20 min and detected with Dako envision flex amplification kit for 30 minutes. Colorimetric detection was completed with Diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that for manual staining we recommend to optimize the primary antibody concentration and incubation time (overnight incubation), and amplification may be required.

Anti-CD35 antibody [E11] - ab76520 from Abcam

Prices $373.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone E11

Anti-CD35 antibody [E11] (FITC) - ab82441 from Abcam

Prices $189.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone E11
Overlay histogram showing peripheral blood lymphocytes stained with ab82441 (red line). The cells incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab82441, 1 µg/1x106 cells) for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 FITC (2 µg/1x106 cells ) for 30 min at 22°C. Acquisition of >5,000 events was performed.

Anti-CD35 antibody [E11] (Phycoerythrin) - ab82439 from Abcam

Prices $372.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone E11

Anti-CD35 antibody [E11] (Phycoerythrin) - ab178451 from Abcam

Prices $370.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone E11

Anti-CD35 antibody [E11], prediluted - ab74318 from Abcam

Prices $378.00
Sizes 7 ml
Host Mouse
Clonality Monoclonal
Clone E11
Cell membrane staining of follicular dendritic cells, B cells and granulocytes in formalin-fixed, paraffin-embedded human tonsil tissue sections using ab74318 with a peroxidase-conjugated secondary antibody and a AEC chromogen.

Anti-CD35 antibody [E11], prediluted (FITC) - ab176538 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone E11

Anti-CD35 antibody [EPR6601] - ab133293 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6601
All lanes : Anti-CD35 antibody [EPR6601] (ab133293) at 1/1000 dilutionLane 1 : TF-1 cell lysateLane 2 : human tonsil lysateLysates/proteins at 10 µg per lane.

Anti-CD35 antibody [EPR6602] - ab126737 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6602
All lanes : Anti-CD35 antibody [EPR6602] (ab126737) at 1/1000 dilutionLane 1 : TF1 lysateLane 2 : Human tonsil lysateLysates/proteins at 10 µg per lane.SecondaryGoat-anti-rabbit HRP at 1/2000 dilutiondeveloped using the ECL technique

Anti-CD35 antibody [RLB25] - ab49520 from Abcam

Host Mouse
Clonality Monoclonal
Clone RLB25
Immunohistochemical staining of paraffin embedded human tonsil tissue using ab49520 at 1/40 dilution, following antigen retrieval. 60 minutes primary antibody incubation at 25oC and standard ABC technique used. Note intense membrane staining of B lymphocytes predominantly within the germinal centers.

Anti-CD35 antibody [SP197] - ab183359 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone SP197
Anti-CD35 antibody [SP197] (ab183359) at 1/400 dilution + Human tonsil lysate

Anti-CD35 antibody - N-terminal - ab200440 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD35 antibody - N-terminal (ab200440) at 1/1000 dilutionLane 1 : mouse thymus extractLane 2 : Jurkat cell extract

Anti-CR1 / CD35 Antibody - LS-C4980 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CR1 / CD35 Antibody (PE) - LS-C4987 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CR1 / CD35 Antibody - LS-C4984 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CR1 / CD35 Antibody (FITC) - LS-C4985 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CR1 / CD35 Antibody (FITC) - LS-C4989 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
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