Gene Symbol | Pgam1 |
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Entrez Gene | 18648 |
Alt Symbol | 2310050F24Rik, Pgam-1 |
Species | Mouse |
Gene Type | protein-coding |
Description | phosphoglycerate mutase 1 |
Other Description | BPG-dependent PGAM 1|PGAM-B|phosphoglycerate mutase isozyme B |
Swissprots | Q9D6W0 Q9DBJ1 Q9ERT3 |
Accessions | CBX85911 EDL41865 Q9DBJ1 AF283667 AAG13955 AK004921 BAB23672 AK008665 AK009905 BAB26576 AK144681 AK150716 BAE29794 AK152443 BAE31223 AK153202 BAE31802 AK159305 BAE34975 AK165410 BAE38168 AK168949 BAE40755 AK180741 AK185826 AK190024 AK190271 AK192318 AK192398 AK192835 AK194151 AK195142 AK195515 AK195806 AK196598 AK197386 AK197934 AK199467 AK203493 AK206956 AK211756 AK212069 AK212756 AK212944 AK214477 AK215282 AK216443 AK218196 AK218874 AK219760 BC002241 AAH02241 BC005661 AAH05661 BC066844 AAH66844 BC067412 AAH67412 BC083090 AAH83090 BC106139 AAI06140 BP769634 NM_023418 NP_075907 |
Function | Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. |
Tissue Specificity | In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues. |
Top Pathways | Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism, Central carbon metabolism in cancer, Glucagon signaling pathway, Biosynthesis of amino acids |
PGAM1 CRISPR/Cas9 KO Plasmid (m) - sc-422210 from Santa Cruz Biotechnology
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PGAM1 HDR Plasmid (m) - sc-422210-HDR from Santa Cruz Biotechnology
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PGAM1 Double Nickase Plasmid (m) - sc-422210-NIC from Santa Cruz Biotechnology
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PGAM1 Double Nickase Plasmid (m2) - sc-422210-NIC-2 from Santa Cruz Biotechnology
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PGAM1 CRISPR Activation Plasmid (m) - sc-422210-ACT from Santa Cruz Biotechnology
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PGAM1 CRISPR Activation Plasmid (m2) - sc-422210-ACT-2 from Santa Cruz Biotechnology
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PGAM1 Lentiviral Activation Particles (m) - sc-422210-LAC from Santa Cruz Biotechnology
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PGAM1 Lentiviral Activation Particles (m2) - sc-422210-LAC-2 from Santa Cruz Biotechnology
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PGAM1 siRNA (m) - sc-62782 from Santa Cruz Biotechnology
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PGAM1 shRNA Plasmid (m) - sc-62782-SH from Santa Cruz Biotechnology
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PGAM1 shRNA (m) Lentiviral Particles - sc-62782-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU196531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN38591 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38591 from Sigma-Aldrich
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PGAM1 siRNA (Mouse) - CRM3041 from Cohesion Biosciences
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shRNA set against Mouse Pgam1 (NM_023418.2) - SHH374084 from Creative biogene
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shRNA set against Mouse Pgam1(NM_023418.2) - SHR108232 from Creative biogene
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PGAM1 shRNA Plasmid (Mouse) - CHM3041 from Cohesion Biosciences
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PGAM1 miRNA 3'UTR clone - MiUTR1M-09135 from Creative biogene
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